云南高校图书馆联盟文献共享服务平台- PHOSPHODIESTER

PHOSPHODIESTER: 作品数：15被引量：9H指数：2; 导出分析报告; 相关领域：理学生物学更多>>; 相关期刊：《Journal of Ocean University of China》《Science China Chemistry》《物理化学学报》《Chinese Journal of Structural Chemistry》更多>>; 相关基金：国家自然科学基金广东省自然科学基金上海市自然科学基金国家重点基础研究发展计划更多>>

Targeting Tyrosyl-DNA phosphodiesterase I to enhance toxicity of phosphodiester linked DNA-adducts被引量：1: 《Cancer Drug Resistance》2019年第4期1153-1163,共11页Evan J.Brettrager Robert C.A.M.van Waardenburg; RCAMvW was in part funded by American Cancer Society UAB ACS-IRG Junior Faculty Development Grant(ACS-IRG-60-001-53);Department of Defense OCRP pilot award W81XWH-15-1-0198;the National Institutes of Health Cancer Center Core Support Grant(P30CA013148).; Our genomic DNA is under constant assault from endogenous and exogenous sources,which needs to be resolved to maintain cellular homeostasis.The eukaryotic DNA repair enzyme Tyrosyl-DNA phosphodiesterase I(Tdp1)catalyz...; 关键词：Tdp1 small molecules DNA topoisomerases CAMPTOTHECINS oxidative DNA damage DNA adducts ETOPOSIDE chain terminating nucleotides/nucleoside analogs DNA metabolism drug development

Synthesis and Crystal Structures of Two Di-Cu(Ⅱ) Complexes Based on an Asymmetric Dinucleating Ligand: 《Chinese Journal of Structural Chemistry》2014年第4期612-618,共7页吴爱芝王涛祝晨蔯; Two new dicopper（II） complexes [Cu2L（OAc）2]（ClO4）·H2O （1） and [Cu2L（BPP）2]-（ClO4）（2） using an asymmetric dinucleating ligand HL and auxiliary ligands such as acetate （OAc） and bisphenyl phosphate （...; 关键词：crystal structure dicopper（II） complexes carboxylate and phosphodiester bridges

Synthesis and biological evaluation of peptide-siRNA conjugates with phosphodiester unit as linker: 《Science China Chemistry》2013年第11期1542-1549,共8页WANG XiaoFeng HUANG Ye LIU Yang CHEN Yue JIN HongWei ZHENG Yi DU Quan YANG ZhenJun ZHANG LiHe; supported by the National Natural Science Foundation of China(20932001);the Ministry of Science and Technology of China(2012AA022501);the National Key Basic Research Program of China(2012CB720604); In this paper,a series of peptide-siRNA conjugates with phosphodiester unit as the linker targeting to Cdc2 gene were synthesized by solid phase stepwise strategy.The conjugation of peptides at either 3’-terminus of ...; 关键词：SIRNA PEPTIDE conjugate solid synthesis

Effective Homogeneous Hydrolysis of Phosphodiester and DNA Cleavage by Chitosan-copper Complex: 《Chinese Journal of Chemistry》2011年第4期711-718,共8页张琦相艳杨汝新司江菊郭红; Project supported by the National Natural Science Foundation of China （Nos. 20403002, 20773008）, the Beijing Novel Program （No. 2008B 12） and the National High-Tech R＆D Program （No. 2007AA05Z146）.; We aimed to explore the role of chitosan-based metal complexes in catalyzing the hydrolysis of phosphodiesters To this end, we performed detailed studies on the kinetics of the chitosan copper complex （CSCu）-catalyz...; 关键词：homogeneous catalysis CHITOSAN copper KINETICS PHOSPHODIESTER HYDROLYSIS

Coorperativity between Metals,Ligands and Solvent：a DFT Study on the Mechanism of a Dizinc Complex-Mediated Phosphodiester Cleavage: 《物理化学学报》2010年第4期1034-1042,共9页FAN Yu-Bo GAO Yi-Qin; 关键词：锌磷酸二酯酶密度功能溶解

DNA Cleavage Promoted by Cu^2＋ Complex of N,N＇-Bis（2-aminoethyl）-2,6-pyridinedicarboxamide: 《Chinese Journal of Chemistry》2007年第7期937-941,共5页李英盛欣邵莺陆国元; Project supported by the National Natural Science Foundation of China （No. 20372032） and the Analytical Foundation of Nanjing University.; The interaction of Cu^2＋ complex of N,N＇-bis（2-aminoethyl）-2,6-pyridinedicarboxamide （BAP） with DNA was studied by agarose gel electrophoresis analysis. The results indicate that the BAP-Cu^2＋ complex can promo...; 关键词：DNA cleavage phosphodiester bond ELECTROPHORESIS nuclease model

Immunogenicity and safety of liposome-vaccine encapsulating hepatitis B surface antigen and phosphodiester CpG oligodeoxynucleotides: 《Journal of Microbiology and Immunology》2006年第2期100-109,共10页CHUN YAN HE QING LIANG LIU; CpG oligodeoxynucleotides （CpG ODN） as adjuvant have been extensively studied in recent years. Phosphodiester CpG ODN （PO CpG ODN） can perfectly mimic bacterial DNA in enhancing immune response but are vulnerable ...; 关键词：CpG oligodeoxynucleotide Phosphodiester Hepatitis B surface antigen Liposome

Polymers with Phosphodiester Bonds:from Models of Biopolymers to Liquid Membranes and Polymerinorganic Hybrids: 《复旦学报（自然科学版）》2005年第5期637-639,共3页Stanislaw Penczek; 关键词：生物高聚物聚合体液体膜分子结构

Rapid Phosphodiester Hydrolysis Catalyzed by Lanthanum（Ⅲ）: 《Chinese Journal of Chemistry》2005年第10期1303-1308,共6页寇兴明胡艳黄忠孟祥光曾宪诚; Project supported by the National Natural Science Foundation of China （Nos. 20173038, 20107004）.; The catalytic hydrolysis of bis（4-nitrophenyl）phosphate （BNPP） by lanthanum（Ⅲ） ion in the presence of amino-alcoholic ligands： diethanolamine （DEA） and triethanolamine （TEA）, was investigated kinetically a...; 关键词：PHOSPHODIESTER HYDROLYSIS lanthanum（Ⅲ） ion amino-alcohol artificial nuclease kinetics

Hydrolysis Activities of the Particle of Agarose-Ce^(4+) Complex for Compounds Containing Phosphodiester or Peptide Bonds被引量：2: 《Journal of Ocean University of China》2005年第3期272-275,共4页YU Lina WANG Dongfeng SU Lin LUO Yi SUN Liping XUEChanghu; supported by the R and D Project Fund of Qingdao(03-2-HH-3);the Natural Science Foundation of Shandong(Z 2004D05); Hydrolysis activities of PACC (particle of agarose-Ce4+ complex, newly made through double emulsification) forcompounds containing phosphodiester or peptide bonds were studied. The results showed that PACC could hydro...; 关键词：particle of agarose-Ce^4＋ complex hydrolyzation organophosphorous pesticide protein

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