150例脑血管病患者死亡时间昼夜节律特点的观察  

Circadian variation rhythm of time of cerebrovascular death in 150 cases

作　　者：王春雪[1] 王琰[1] 温淼[1] 李菁菁[1] 崔涛[1] 王拥军[1] 

机构地区：[1]首都医科大学附属北京天坛医院神经内科,北京100050

出　　处：《中华老年心脑血管病杂志》2003年第5期322-324,共3页Chinese Journal of Geriatric Heart,Brain and Vessel Diseases

摘　　要：目的　探讨脑血管病患者死亡时间的昼夜节律变化特点和规律。方法　回顾性分析 15 0例脑血管病患者死亡病例的临床资料 ,并重点分析死亡时间 ,利用圆形分布的统计方法 ,计算出死亡高峰时刻和 2 4h内 95 %的死亡时间集中时段。结果　脑血管病患者死亡高峰时刻为 0 5 :5 9:5 6 ,2 4h内 95 %的死亡时间发生在 2 0 :2 1:5 8至第二天15 :37:5 4 ;其中出血性脑血管病患者的死亡高峰时刻为 0 6 :2 0 :4 8,2 4h内 95 %的死亡时间发生在 0 1:4 0 :15至11:0 1:2 1;缺血性脑血管病患者的死亡高峰时刻为 0 5 :5 9:31,2 4h内 95 %的死亡时间发生在 0 1:0 4 :2 3至 10 :5 4 :39。结论　脑血管病患者的死亡时间有一定的昼夜节律分布的特点 。Objective To Analyze the time of death in 150 cases of stroke patients retrospectively and to find out the circadian rhythm of cerebrovascular death in order to provide helpful information for clinical practice.Methods The time of death of 150 cases was analyzed by mathematical statistics.The peak time of death and the period of 95% deaths in 24 hours daily were calculated.Results The peak time of stroke death was at 05:59:56 and 95% deaths in 24 hours was located in the period from 20:21:58 to 15:37:54 of the next day.Moreover,the peak time of hemorrhagic stroke death was at 06:20:48 and 95% deaths in 24 hours occurred from 01:40:15 to 11:01:21. While for ischemic stroke, the risky time of death was at 05:59:31 and the 95% deaths in 24 hours occurred between 01:04:23 to 10:54:39.Conclusions Circadian rhythm of cerebrovascular death was noticed in this study. The risky peak time of death in stroke patients was always in the early morning. However, neurologists should consider both individual variation and medical intervention for the individual patient in evaluating the time of death. Meanwhile, clinical staff should pay more attention to monitor stroke patients in the early morning and modify some medical remedies if necessary.

关 键 词：脑血管意外 昼夜节律 脑出血 脑梗塞 

分 类 号：R743.3[医药卫生—神经病学与精神病学]