芬太尼、罗比卡因配伍用于直肠癌术后硬膜外镇痛的临床观察  

Postoperative epidural analgesia with fentanyl and ropivacame after rectal carcinoma

作　　者：隋成[1] 李键[1] 姜万维[1] 宋永利[1] 宋稀斌[1] 姚小鹏[1] 

机构地区：[1]大连大学附属医院,辽宁大连116021

出　　处：《大连大学学报》2003年第4期104-106,共3页Journal of Dalian University

摘　　要：[目的]研究芬太尼、罗比卡因配伍用于硬膜外术后镇痛的临床效果及不良反应。[方法]ASAI-Ⅱ级择期直肠癌切除术患者60例,按术后硬膜外用药的不同随机分为两组,每组30例、Ⅰ级(观察组)术后硬膜外用药为2ml/h微量止痛泵加入0.2％罗比卡因100ml、芬太尼0.2mg,Ⅱ组(对照组)术后硬膜外用药为2ml/h微量止痛泵中入0.25％布比卡因100ml、芬太尼0.2mg术后行视觉模拟评分(VAS)(Visual analogue scale),BCS(bruggrmann comfort scale)舒适评分并观察不良反应发生情况。[结果]Ⅰ组VAS评分明显低于对照组(P<0.05或P<0.01)。BCS评分明显高于对照组(P<0.05或P<0.01)。两组均无术后不良反应发生。[结论]芬太尼、罗比卡因配伍硬膜持续应用可获得良好的术后镇痛效果。[Objective) To study the analgesic effects and side effects of epidural analgesia with fentany and ropivacame. [Methods) Sixty ASA Ⅰ-Ⅱ patients were randomly divided into two groups. In each group were 30 patients, Group Ⅰ (observe) received epidural injection with 2ml/h infusion pump with 0.2% ropivacame 100ml and fentany 0.2ml after operations. Group Ⅱ (Model) received epidural injetion with 0.25% bupivacaine 100ml and fentany 0.2mg after operations. The visual analogue scale(VAS) and bruggrmann comfort scale(BCS) were done either at the same time points in two groups, the incidence of side effects was recorded. [Results) The VAS scores of Group I are significantly less than those of Group n (P<0.05 or P<0.01) . The BCS scores of Group I is significantly increased than those of Group n (P<0.05 or P<0.01) . Neither two groups have side effects after operations. [Conclusions] The combination of fentany ropivacame may produce a longer postoperative analgesic duration.

关 键 词：芬太尼:罗比卡因 微量止痛泵:硬膜外 术后镇痛 直肠癌 配伍 

分 类 号：R735.37[医药卫生—肿瘤] R614.42[医药卫生—临床医学]