男性不育者精子顶体酶活性影响因素分析  

Analysis of Influence Factors of Human Sperm Acrosin Activity

作　　者：刘睿智[1] 沙艳伟[1] 许宗革[1] 董乃屹 辛暨丽[1] 李哲[1] 王忠山[1] 

机构地区：[1]吉林大学基础医学院细胞生物学教研室,吉林长春130021 [2]吉林省计划生育研究所

出　　处：《吉林大学学报（医学版）》2003年第5期567-569,共3页Journal of Jilin University：Medicine Edition

基　　金：吉林省计划委员会资助课题 (1999)

摘　　要：目的 :分析某些因素对男性不育者精子顶体酶活性的影响。方法 :分光光度比色法检测3767例男性不育者精子顶体酶活性。结果 :精液液化时间延长组、p H值降低组、白细胞数 >5个 /HP组的精子顶体酶活性均显著低于其相应对照组 ( P<0 .0 0 1 ,P<0 .0 0 1 ,P<0 .0 5 )。顶体酶活性与支原体感染和精浆 As Ab无关 ( P>0 .0 5 ,P>0 .0 5 )。结论 :精液液化时间、p H值和白细胞数影响顶体酶活性 ,精液支原体感染和精浆 AsObjective:In order to study the influence factor of the sperm acrosin activity. Methods:The sperm acrosin activities in 3 767 male infertiles were determined and the influence factors were analyzed. Results:There was a significant difference in normal semen liquefied duration, pH and white blood cells (WBC) under microscope ( P <0.001, P <0.001, P <0.05). The comparison between U.urealyticum negative group and U.urealyticum positive group showed that the acrosin activity was not significant difference ( P >0.05). The comparison between AsAb positive group and AsAb negative group showed the acrosin activity was not significant difference ( P >0.05).Conclusion:Semen liquefied duration, pH and WBC could affect acrosin activity. U.urealyticum infection in semen and AsAb in seminal plasma could not affect acrosin activity. [

关 键 词：不育 男性 酶学 精子 顶体蛋白酶 支原体感染 并发症 解脲脲原体 抗精子抗体 

分 类 号：R698.2[医药卫生—泌尿科学]