精神分裂症患者及其亲属免疫学研究  

A study of molecular immunology among schizophrenic patients and their relatives

作　　者：陈海支[1] 李新胜[1] 尹刚[1] 徐静[1] 刘晓华[1] 

机构地区：[1]湖北十堰市东风公司茅箭医院,442012

出　　处：《临床精神医学杂志》2003年第5期277-278,共2页Journal of Clinical Psychiatry

摘　　要：目的 :了解散发性首发精神分裂症患者及其一级亲属免疫球蛋白及补体成份与正常人是否存在差异。　方法 :用免疫透射比浊法测精神分裂症患者及其一级亲属及健康者血清中免疫球蛋白及补体成份的含量 ,并相互比较。　结果 :精神分裂症患者及其一级亲属IgA、IgG及C4显著高于正常人(P <0 .0 5～ 0 0 1)。　结论 :精神分裂症患者及其一级亲属存在同样免疫学异常 。Objective:To investigate whether there are differences of the molecular immunology among schizophrenic patients and their first degree relatives of sporadic schizophrenia Method:Immunoturbidimetry was used to example the IgA,IgG,IgM,C 3,C 4 in serum of schizophrenics and their first degree relatives and compared them with those of normal controls. Results:IgA,IgG,C 4 in both of the schizophrenics and their first degree relatives were significantly higher than those in the normal controls. Conclusion:The sporadic first-episode schizophrenics and their first degree relatives have immunology dysfunction which might be in relative to the factor of genetics.

关 键 词：精神分裂症 一级亲属 免疫球蛋白 补体 

分 类 号：R749.3[医药卫生—神经病学与精神病学]