喉癌患者血小板聚集功能的测定  

Measurement of platelet aggregation in patients with lar yngeal carcinoma

作　　者：姚宪义[1] 周彬[1] 王振霖[1] 王丽妍[1] 李玉春[1] 

机构地区：[1]哈尔滨医科大学第一临床医学院耳鼻咽喉科,黑龙江哈尔滨150001

出　　处：《哈尔滨医科大学学报》2003年第5期431-432,共2页Journal of Harbin Medical University

摘　　要：目的　探讨喉癌与血小板聚集功能的关系。方法　采用比浊法 ,对 5 0例喉癌患者进行血小板聚集功能的检测并以良性肿瘤病人、喉慢性炎性疾病病人及正常人作为对照 ,应用SAS计算机系统进行分析。结果　与其他组病人相比 ,喉癌组血小板聚集功能增强并且随着临床分期的增高有增强趋势。结论　喉癌病人的血小板聚集功能有一定的增强 ;测定血小板聚集功能对恶性肿瘤的疗效判定、预后评估及预测转移有一定的意义 ;血小板抑制剂有望成为治疗肿瘤的新方法。Objective To investigate the relationship between the platelet ag gregation and laryngeal carcinoma in patients with laryngeal carcinoma. Methods Platelet aggregation tests(PAgT) were performed in 50 patie nts with laryngeal carcinoma,20 persons with benign tumors of the larynx,40 chronic laryngitis and 50 normal persons as controls. Results The maximum aggregation rates of the platelets in patients with laryngeal carcinoma were significantly higher than those in other groups;th e mean of MAR increased with the development of tumor stages. Conclusion The platelet aggregation increase in patients with lary ngeal carcinoma;the platelet aggregation test has an important value in judging the development,therapeutic effects and prognosis of the laryngeal carcinoma.

关 键 词：喉癌 血小板聚集功能 测定 肿瘤转移 血小板抑制剂 

分 类 号：R739.65[医药卫生—肿瘤]