草酸铂为主联合方案动脉介入治疗晚期肠癌  

Treatment of advanced and metastasis colorectal cancer with combined chemotherapy based on oxaliplatin b y intervening arterial chemotherapy

作　　者：惠锦林[1] 王彬[1] 梅蔚德[1] 

机构地区：[1]安徽省新华肿瘤医院,合肥230051

出　　处：《安徽卫生职业技术学院学报》2003年第5期33-34,共2页Journal of Anhui Health Vocational & Technical College

摘　　要：目的:总结探讨草酸铂为主方案动脉介入治疗晚期直肠癌近期疗效及毒副反应。方法:12例晚期直肠癌(Ⅲ～Ⅳ期)经股动脉插管至髂内、外动脉,肝动脉介入艾恒、5-Fu、CF、OHCPT、IFN联合化疗。治疗两周期评价疗效及相关症状改善(DRSI)及毒副反应。结果:经治疗PR7例(58.33%),NC5例(41.67%)。12例相关症状改善,毒副反应可耐受,未见严重不可逆反应。结论:草酸铂为主方案介入化疗方法治疗晚期肠癌复发或肝脏转移患者,安全有效,毒副作用小,明显改善患者症状,提高生存质量。Objective To investigate the efficacy of combi ned chemotherap y based on oxaliplatin by intervening ar-terial,for treatment of relapse and m etastasis colorectal cancer and its side-effect.Methods12cases of relapse a nd metastasis colorectal cancer by int ervening arterial chemotherapy,based on oxaliplatin and 5-Fu?CF?OHCPT?IFN,after 2cycles of treatment,the efficac y and clinical symptoms were evaluated.Results After treatment,seven obtained PR,five NC,twelve symptoms related to cancer improved and side-reactio ns ar e tolerable;:Conclusion Treatment of relapse andmetastasis colorectalc ancer w ith combinedchemotherapy basedon oxaliplatinby intervening artery,safe and effe ctive;with only slight side-effects.This treatment can improve th e symptoms and life quality of patien t effectively.

关 键 词：复发转移性肠癌 草酸铂 动脉介入化疗 

分 类 号：R735.305[医药卫生—肿瘤]