深圳市1994～2002年急性弛缓性麻痹病例发病情况  

The morbidity of acute flaccid paralysis (AFP) in Shenzhen in 1994～2002

作　　者：谭洁[1] 吴坤森[1] 袁芝琴[1] 单芙香[1] 苏小宏[1] 蔡创辉[1] 

机构地区：[1]广东省深圳市疾病预防控制中心,518020

出　　处：《职业与健康》2003年第10期88-90,共3页Occupation and Health

摘　　要：目的　为了全面了解深圳市急性弛缓性麻痹 (AFP)病例发病情况回顾性调查。方法　采用回顾性调查方法 ,利用1994～ 2 0 0 2年AFP个案资料 ,对AFP病例的地区分布 ,时间分布 ,免疫史 ,性别 ,年龄 ,60d随访结果等进行流行病学分析。结果　 1994～ 2 0 0 2年 15岁以下儿童AFP病例报告发病率达到 1/10万 ,共报告 12 7例 ,全市 6个区均有病例报告 ,病例主要集中在小年龄组 ,小于 3岁的占 71 7% ,发病季节不明显 ,男女性别比例为 1 64∶1,AFP病例主要以格林 -巴利综合征 ,创伤性神经炎或疫苗相关病例 (VAPP)为主。结论　深圳市 1994～ 2 0 0 2年未发现由脊髓灰质炎 (脊灰 )野病毒引起的病例。疫苗相关株是引起残留麻痹的主要原因 ,实现无脊灰后VAPP的影响不容忽视。龙岗区、宝安区、南山区需加强AFP监测工作。To learn the morbidity of acute flaccid paralysis (AFP) in Shenzhen.Retrospective investigation method was adopted to make epidemiological analysis on the area distribution, time distribution, immunization history, sex and age for 60 days according to the AFP data in 1994～2002.The morbidity of AFP among children under 15 years old was 1/100 000 with 127 reported cases. The age distribution was mainly 0～3 years old children. Time distribution showed no obvious seasonal difference. The ratio of male to female was 1.64:1. AFP cases were mainly Guillain-Barre syndrome, traumatic neuritis and vaccine associated paralytic poliomyelitis (VAPP).[Conclusion]No polio caused by wild poliovirus was found in Shenzhen in 1994～2002. Vaccine associated strains were the main cause for remained paralysis. The effect of VAPP shouldn't be neglected. AFP supervision should be strengthened in Longgang, Baoshan and Nanshan districts.

关 键 词：急性弛缓性麻痹 发病率 深圳市 1994~2002年 流行病学调查 脊髓灰质炎 

分 类 号：R741.041[医药卫生—神经病学与精神病学]