重复经颅磁刺激对正常人定量脑电图的影响  

Effect of repetitive transcranial magnetic stimulation on quantitative electroencephalogram of health subjects

作　　者：王晓明[1] 谢建平[1] 张丽兰[1] 赵小琼[1] 陈志琼[1] 

机构地区：[1]川北医学院附属医院神经内科和神经电生理研究室,四川省南充市637000

出　　处：《中国临床康复》2003年第28期3820-3821,共2页Chinese Journal of Clinical Rehabilitation

基　　金：四川省教委科研基金(99川教计164); 四川省青年基金预研项目(03ZQ026-069)~~

摘　　要：目的:探讨重复经颅磁刺激(repetitivetranscranialmagneticstimulation,rTMS)对正常人脑电活动的影响及其安全性。方法:对12名健康受试者左额叶予20Hz,100次/串、共5串、100%运动阈值的rTMS,并观察其刺激前后定量脑电图(qEEG)变化。结果:正常人rTMS后短时间内左额区β波频率增加刺激前β波为主者2名(2/12),刺激后8名(8/12)(χ2=4.285,P<0.05);磁刺激前后各脑区的δ,θ,α,β频带的绝对功率值差异无显著性意义(P>0.05),各脑区(δ+θ)/(α+β)比值无明显改变(t=1.433～2.132,均P>0.05),刺激过程中无明显不适。结论:rTMS对健康人脑电活动有一定调节作用,在一定强度和频率内rTMS是一种比较安全的方法。AIM:To explore the effects of repetitive transcranial magnetic stimulation(rTMS )on quantitative electroencephalogram(qEEG)of health subjects and to assess the safety of rTMS.METHODS:rTMS was performed in 12healthy volu nteers,with the fre-quency of 20Hz,100times for one cour se,for 5courses.qEEG was ana-lyzed before and after rTMS.RESULTS:The frequency of βwave in left frontal was increased in eight of twelve volunteers as compared with t wo of twelve volunteers before treat ment (χ 2 =4.285,P<0.05),and the ratio of(δ+θ)/(α+β)was no signifi-cant difference after stimulation(t=1.433-2.132,P>0.05).

关 键 词：重复经颅磁刺激 RTMS 人 QEEG 定量脑电图 脑电活动 

分 类 号：R741.044[医药卫生—神经病学与精神病学]