原发性腹膜恶性肿瘤28例临床分析  

Primary Peritoneal Malignant Tumor: Clinical Analysis of 28 Cases

作　　者：吴燕[1] 李蔚范 

机构地区：[1]北京大学人民医院妇科肿瘤中心,北京100044 [2]北京大学肿瘤医院妇科,北京100036

出　　处：《癌症》2003年第11期1228-1231,共4页Chinese Journal of Cancer

摘　　要：背景与目的:原发性腹膜恶性肿瘤是一种临床上少见的肿瘤,其形态学及临床表现与晚期卵巢癌十分相似,常常因误诊而延误治疗。本研究的目的是通过分析28例原发性腹膜恶性肿瘤的临床特点、诊断、治疗及其预后,以提高对该病的认识。方法:对1996年1月～2002年2月我院收治的28例原发性腹膜恶性肿瘤患者的临床资料进行回顾性分析。结果:原发性腹膜浆液性乳头状腺癌20例,原发性腹膜恶性混合苗勒氏管肿瘤8例;患者年龄33～74岁,中位年龄54岁。28例中术前22例误诊,误诊率为79％;全部病例均行细胞减灭术;术后GAP方案或TP方案化疗。术后生存时间为1～83个月,中位生存时间为30个月。结论:应提高对原发性腹膜恶性肿瘤临床特点的认识,早期诊断,及时进行肿瘤细胞减灭术,术后辅助化疗,提高其生存率。BACKGROUND & OBJECTIVE: Primary malignant peritoneal tumor is a kind of rare malignancy. Its morphology and clinical manifestations are very similar to the advanced ovarian cancer, therefore, they are usually misdiagnosed and the proper treatment were delayed. This paper analyzed the clinical characteristics, diagnosis, treatment, and prognosis of primary malignant peritoneal tumor. METHODS: The clinical data of 28 cases of primary peritoneal malignant tumor patients admitted between January 1996 to February 2002 in People's Hospital, Peking University, was analyzed retrospectively. There are 20 cases of primary peritoneal seropapillary adenocarcinoma, 8 cases of primary peritoneal malignant Muellerian tube tumor. Their age ranged from 33 to 74, with median age of 54. RESULTS: Among 28 patients, 22 were misdiagnosed preoperatively, the misdiagnose rate were 79%. In all cases, cytoreductive surgery were performed. Postoperative chemotherapy were given either with CAP regimen or TP regimen. Postoperative survival time was 1-83 months, the median survival time was 30 months. CONCLUSION: The recognition of this special tumor should be stressed, to improve early diagnosis and treatment. The authors suggest that cytoreductive surgery on time and postoperative adjuvant chemotherapy should be implemented to improve survival rate.

关 键 词：原发性腹膜恶性肿瘤 临床特点 诊断 治疗 预后 

分 类 号：R735.5[医药卫生—肿瘤]