恶性淋巴瘤危险因素病例对照研究  

A Case-control Study on Risk Factors of Malignant Lymphoma

作　　者：蓝绍颖[1] 任金马[1] 

机构地区：[1]南通医学院卫生系,江苏南通226001

出　　处：《中国肿瘤》2003年第10期577-579,共3页China Cancer

摘　　要：[目的]探讨恶性淋巴瘤发病的危险因素。[方法]采用1∶2配比病例对照研究的方法,对南通市及其周围地区48例经细胞学或病理学确诊的恶性淋巴瘤患者及96例对照进行问卷调查,相关资料采用条件Logistic回归分析。[结果]三废污染(OR=3.07,90%CI1.23～7.67)、有机溶剂(OR=3.88,90%CI1.18～13.97)、避孕药(OR=2.26,90%CI1.15～6.60)、家族肿瘤史(OR=17.30,90%CI4.42～57.66)和饮酒(OR=0.66,90%CI0.43～1.00)与恶性淋巴瘤的发病有关。[结论]三废污染、有机溶剂、避孕药和家族肿瘤史可能是恶性淋巴瘤的危险因素,而少量饮酒可以降低恶性淋巴瘤的发病危险性。To investigate the risk factors related to malignant lymphoma(ML).A1∶2matched case-control study was carried out with48cases and96controls in Nantong and nearby regions.Information was obtained by questionnaires.Data were analyzed with conditional Logistic regression.Pollution(OR=3.07,90%CI1.23～7.67),organic solvent(OR=3.88,90%CI1.18～13.97),prophylactic(OR=2.26,90%CI1.15～6.60),the family history of cancer(OR=17.30,90%CI4.42～57.66),and drinking(OR=0.66,90%CI0.43～1.00)were related to ML.[Conclusion]Environment pollutions,solvent,contraceptive medicine and family history of cancer seem to be the risk factors of ML,while a little drink consume seem to reduce the occurrence of ML.

关 键 词：淋巴瘤 危险因素 病例对照研究 条件LOGISTIC回归 流行病学 

分 类 号：R73-31[医药卫生—肿瘤]