注意力客观测试对哌醋甲酯干预下ADHD转归的观察  

The observation of objective attention test on the outcome of ADHD treated with methylphenidate

作　　者：茅双根[1] 胡芳[1] 任颖[1] 

机构地区：[1]皖南医学院附属弋矶山医院儿科,241001

出　　处：《皖南医学院学报》2003年第4期276-278,共3页Journal of Wannan Medical College

基　　金：皖南医学院内科研中标课题 (编号弋院字 0 2 7号 )资助

摘　　要：目的　探讨哌醋甲酯 (MPH)干预下注意力缺陷多动症 (ADHD)的转归及注意力缺陷测试仪的应用价值。方法　将 176例ADHD患儿分为两组 ,分别口服MPH 1个月 (治疗Ⅰ组 )和 2个月 (治疗Ⅱ组 ) ,采用NJ2 2注意力缺陷测试仪分别于治疗前、后及停药 1个月后测试患儿注意力缺陷程度及其动态变化 ,比较两组疗效及停药后症状反跳情况。同时应用DSM Ⅳ量表进行对比观察 ,比较两组疗效。结果　治疗Ⅰ组和Ⅱ组的注意力轻度异常患儿显效率分别为 76 %和 82 % ,总有效率分别为 81%和 86 % ,差异均无显著性意义 (P >0 .0 5 ) ;两组的注意力重度异常患儿显效率分别为 17%和 4 8% ,差异有显著性意义 (P <0 .0 1)。采用测试仪及DSM Ⅳ量表两种方法观察 ,一致率为 73.9%。停药 1个月后两组注意障碍反跳率分别为 87%和 81% ,差异无显著意义 (P >0 .0 5 )。结论　MPH治疗ADHD短期效果肯定 ,但必须有完善的多向治疗支持才可能获得满意的远期疗效 ;NJ2Objective To investigate the outcome of attention-deficit hyperactivity disorder (ADHD) treated with methylphenidate (MPH) and the application value of attention-deficit tester. Methods 176 children with ADHD were divided into two groups with all taking MPH orally for 1 month or 2 months respectively. The degrees of patients' attention-deficit and their dynamic variation were detected with NJ22 attention-deficit tester, and the curative effects and the springing after the withdrawal of MPH were compared. The DSM-Ⅳ scale was applied in order to evaluate and compare the curative effects of the two groups. Results The significant effective rates of group Ⅰand group Ⅱ were 76% and 82% , and total effective rates were 81% and 86% , with no significant difference (P>0.05). The effective rates in patients of two groups with severe attention-deficit were 17% and 48% respectively. There was significant difference between the two groups (P<0.05). The rate of coherence was 73.9% when patients were evaluated with tester and DSM-Ⅳ scale. The rates of springing were 87% and 81% in two groups respectively 1 month after the withdrawal of drug (P>0.05). Conclusion The short-term effect of MPH to treat ADHD is obvious,so various kinds of supportive therapies are needed in order to attain satisfactory long-term curative effects. NJ22 attention-deficit tester has objective value for the study of the outcome of ADHD.

关 键 词：注意力 测试 哌醋甲酯 ADHD 临床转归 注意力缺陷多动症 儿童 

分 类 号：R749.94[医药卫生—神经病学与精神病学]