口服枸杞子对人体淋巴细胞辐射抗性的研究  

Study of Fructus Lych on Radiosensitivity Resistivity in Human Lymphocytes

作　　者：文润玲[1] 李国莉[1] 

机构地区：[1]宁夏医学院预防医学系,宁夏银川750004

出　　处：《辽宁中医杂志》2001年第1期60-61,共2页Liaoning Journal of Traditional Chinese Medicine

基　　金：宁夏自治区科委资助课题

摘　　要：随着增龄 ,人体对辐射敏感性的抗性逐渐降低 ,表现在对遗传物质 DNA损伤修复能力 (DNAR)和体内防护物质 ,超氧化物歧化酶、过氧化物酶、过氧化氢酶 (SOD、CAT、POT)等保护酶的活性降低和过氧化脂质(L PO)的升高。枸杞具有抗衰功效 ,并有增强细胞对辐射敏感的抗性作用。利用传统的非程序 DNA合成法 (UPS) ,酶活性测试盒 ,测定了健康人、肿瘤病人 ,以及口服枸杞和枸杞复合多糖后 ,健康人和老年人的 DNAR、SOD、CAT、L PO。结果表明 ,老年人和癌症病人的 DNAR明显降低。口服枸杞能够明显增强人的 DNAR、SOD、CAT,降低L PO。The paper presents that the velocities of ultraviolet-induced 3H-TdR unscheduled incorporation (DNA repair capacity DNAR) in human lymphocytes,and the activities of superoxide mutase(SOD),catalase(CAT) and lipid peroxidase (LPO) were determined from patients of tumor and the aged before and after taking Fructus Lycii.The result showed that DNAR,SOD and CAT were significantly increased and that LPO activity was significantly decreased after taking Fructus Lycii.

关 键 词：枸杞 DNA修复能力 防护酶 基因突变 辐射抗性 

分 类 号：R285.1[医药卫生—中药学]