达乌尔黄鼠冬眠期与非冬眠期的产热活性及激素调节  

THERMOGENIC ACTIVITY AND HORMONAL REGULATION OF DAURIAN GROUND SQUIRREL DURING HIBERNATION AND NONHIBERNATION

作　　者：黄晨西[1] 林琳[1] 李庆芬[1] 

机构地区：[1]北京师范大学生物多样性与生态工程教育部重点实验室,北京100875

出　　处：《北京师范大学学报（自然科学版）》2003年第5期683-687,共5页Journal of Beijing Normal University(Natural Science)

基　　金：国家自然科学基金资助项目 (39970 12 4 )

摘　　要：测定了达乌尔黄鼠 (SpermophilusDauricus)冬季冬眠时和秋季非冬眠时的产热活性及其激素调节 .达乌尔黄鼠下丘脑促甲状腺激素释放激素 (TRH)冬眠时含量显著高于非冬眠时的 ,血清中三碘甲腺原氨酸 (T3)、甲状腺素 (T4 )质量浓度也有明显增加 .表明达乌尔黄鼠下丘脑甲状腺轴激素水平和功能存在季节性变化 ,冬眠时该轴是激活的 ,这个轴的激活 ,有利于黄鼠冬眠觉醒中褐色脂肪组织 (BAT)的产热 .冬眠时达乌尔黄鼠下丘脑促肾上腺激素释放激素 (CRF)的质量分数、肾上腺皮质酮的质量分数和肾上腺质量明显比非冬眠季节的个体低 .表明达乌尔黄鼠在冬眠过程中 ,下丘脑CRF 肾上腺轴受到抑制 ,从而解除了对BAT产热的抑制作用 .Daurian ground squirrel is tested in hibernation (in winter) and non hibernation (in autumn). w (TRH) in Daurian ground squirrels hypothalamus during hibernation is obviously higher than that during nonhibernation. ρ (T 3) and ρ (T 4) in serum have the similar trend with TRH. It suggests that there is a seasonal variety of hormone levels and function of Daurian ground squirrels hypothalamus thyroid gland axis, and that this axis is activated during hibernation. The activity of this axis is helpful to increase the thermogenesis of BAT when hibernating squirrel is aroused. w (CRF) in Daurian ground squirrels hypothalamus, the corticosterone concentration and the weight of adrenal gland during hibernation are significantly lower than during nonhibernation. This result shows that Daurian ground squirrels hypothalamus adrenal gland axis is inhibited during hibernation and the inhibition of this axis to BAT thermogenesis is released.

关 键 词：达乌尔黄鼠 冬眠期 产热活性 激素调节 下丘脑-甲状腺轴 下丘脑-肾上腺轴 啮齿目 

分 类 号：Q959.837[生物学—动物学] Q958.117