丘脑出血伴消化道出血患者血清胃泌素的变化  

Serum Gastrin Level Changes in Patients with Thalamic Hemorrhage Accompanied by Digestive Tract Bleeding

作　　者：陈兴华[1] 李倩[1] 俞丽华[1] 

机构地区：[1]上海第二医科大学新华医院神经内科,上海200092

出　　处：《上海第二医科大学学报》2003年第B10期97-98,共2页Acta Universitatis Medicinalis Secondae Shanghai

摘　　要：目的 探讨丘脑出血伴消化道出血与血清胃泌素的关系。方法 38例丘脑出血患者,其中22例伴消化道出血,16例无消化道出血,采用放射免疫方法检测血清胃泌素水平,并与对照组30例正常人比较。结果 丘脑出血患者的胃泌素水平为(201.0±75.1)ng/L,较正常对照组(81.0±47.2)ng/L明显升高,其中急性期伴消化道出血者胃泌素水平为(224.0±68.8)ng/L,不伴消化道出血者为(164.1±71.1)ng/L,二者之间比较或与正常对照组比较均有显著差异(P<0.01)。结论 胃泌素水平的改变与丘脑出血有关,尤其在急性期和伴消化道出血者明显增高。Objective To study the relationship between thalamic hemorrhage accompanied by digestive tract bleeding and serum gastrin levels. Methods The serum gastrin levels were measured by radio-immunoassay in 38 patients with thalamic hemorrhage (26 males and 12 females; 16 with GI tract bleeding, 22 without GI tract bleeding) and 30 healthy controls. Results The serum gastrin levels in patients with thalamic hemorrhage were increased significantly in comparision with that in controls [ (201. 4±75. 1) ng/L vs(81. 0±47. 2) ng/L,P <0. 01 ]. There were also statistically significant differences between the patients with acute digestive bleeding,the patients with acute digestive bleeding[ (224.0?±68.8) ng/L] or without gastrointestinal tract bleeding [ (164. 1±71. 1) ng/L] and the controls. Conclusion The changes of serum gastrin levels are associated with thalamic hemorrhage, especially in the acute patients and the pati-ente with gastrointestinal tract bleeding.

关 键 词：丘脑出血 消化道出血 血清 胃泌素 

分 类 号：R743.3[医药卫生—神经病学与精神病学]