不同非手术治疗方案对老年性肝癌的疗效评价  

Effect of the different combined therapy methods of transcatheter arterial chemoembolization (TACE) and percutaneous radio-frequency ablation(RF) on the elder patients with unresectable hepatocellular carcinoma(HCC)

作　　者：宋斌[1] 王卫星[1] 张文[2] 杨威[3] 

机构地区：[1]武汉大学人民医院普外科,430060 [2]西安交通大学医学院 [3]第一医院普外科

出　　处：《肿瘤防治研究》2003年第6期496-497,501,共3页Cancer Research on Prevention and Treatment

摘　　要：目的　探讨射频消融 (RF)术前行肝动脉化疗栓塞 (TACE)与RF术后行TACE两种联合治疗方案对老年性不可切除性肝癌的疗效。方法　将接受TACE与RF联合治疗的 6 9例不可切除性老年性肝癌患者分为两组。一组为TACE +RF组 ,35例 ;另一组为RF +TACE组 ,34例。分别将两组治疗后肿瘤缩小率 ,消融率 ,瘤周血流信号 ,AFP值及治疗后 6个月、12个月生存率进行对比。结果　两组间前述 5种指标均具有显著性差异 ,TACE +RF组优于RF +TACE组。结论　对于老年性不可切除性肝癌患者提倡采用TACE +RF联合治疗方案 ,即RF术前先行TACE ,以增强两治疗方法之间互补性与疗效。Objective To evaluate the effect of the different combined therapy methods of transcatheter arterial chemoembolization (TACE) and percutaneous radio-frequency ablation (RF) on the elder patients with unresectable hepatocellular carcinoma (HCC).Methods 35 unresectable elder HCC patients received the combined therapy of TACE before RF (group TACE+RF). 34 unresectable elder HCC patients received the combined therapy of TACE after RF (group RF+TACE). The datas of color-ultrasonography, AFP, 6-months and 12-months survival rate of two groups were compared. Results There was remarkable difference in these datas of two groups.Conclusion The combined method of TACE+RF is more effective.

关 键 词：非手术治疗 肝癌 疗效评价 射频消融 肝动脉化疗栓塞 老年人 

分 类 号：R735.7[医药卫生—肿瘤]