正常人重复经颅磁刺激后脑血流速度的变化  

Changes of cerebral blood flow velocity after repetitive transcranial magnetic stimulation in health subjects

作　　者：王晓明[1] 谢建平[1] 黄慧[1] 赵晓琼[1] 胡建秀[1] 

机构地区：[1]川北医学院附属医院神经内科和神经电生理研究室,南充637000

出　　处：《临床神经电生理学杂志》2003年第4期202-203,共2页Journal of Clinical Electroneurophysiology

基　　金：四川省教委科研基金 ( 99川教计 164 );四川省科技厅科研基金 ( 0 2SG0 2 2 0 10 )

摘　　要：目的 :探讨重复经颅磁刺激 (rTMS)对正常人脑血流速度的影响。方法 :对 12位健康受试者左额叶进行高频rTMS ,并用经颅多普勒超声仪 (TCD)观察其脑血流速度变化。结果 :正常人rTMS后 ,除左右大脑后动脉及椎动脉外 ,平均血流速度 (Vm)均有不同程度的增加 ,以左侧大脑前动脉及左侧大脑中动脉Vm的增加尤为明显 (P <0 0 5 ) ;刺激过程中无明显不适。结论 :rTMS能增加脑血流速度 ,且在一定的刺激强度和刺激频率范围内 。Objective:To explore the effects of repetitive transcranial magnetic stimulation(rTMS) on cerebral blood flow velocity of health subjects Methods:rTMS was performed in 12 healthy volunteers,the mean cerebral blood flow velocity(Vm) were determined by transcranial doppler(TCD) before and after rTMS.Results:Vm increased significantly in bilateral anterior cerebral artery and left middle cerebral artery,especially in the left anterior cerebral artery.Uncomfortable sensation was not noted during stimulation.Conclusions:rTMS might increase the cerebral blood flow velocity,rTMS might be safe under the range of certain intensity and frequency of stimulation.

关 键 词：磁刺激 电生理学 经颅多普勒超声 血流速度 大脑后动脉 椎动脉外 

分 类 号：R743.1[医药卫生—神经病学与精神病学]