多系统萎缩者脑干诱发电位的检测  

Alteration of Brainstem Auditory Evoked Potentials in Multiple System Atrophy

作　　者：应智林[1] 张宝荣[1] 程源深[1] 周宝礼[1] 虞晓青[2] 

机构地区：[1]浙江大学医学院附属第二医院,浙江杭州310009 [2]杭州武警医院,浙江杭州310004

出　　处：《浙江大学学报（医学版）》1999年第5期215-216,226,共3页Journal of Zhejiang University(Medical Sciences)

摘　　要：目的：研究多系统萎缩对脑干功能的影响。方法：用电生理多用诊断仪对２９例橄榄－桥脑－小脑萎缩（ＯＰＣＡ）、１０ 例直立性低血压（ＳＤＳ）和１９例健康志愿者（对照组）的脑干诱发电位进行检测。结果：ＯＰＣＡ及ＳＤＳ的Ⅰ～Ⅴ波有不同程度的缺失、结构紊乱和不对称性，Ⅴ波的潜伏期分别为６．５０±０．９０ ｍ ｓ及６．４４±０．７９ ｍ ｓ，较对照组（５．８７±０．３７ ｍ ｓ）延长（Ｐ＜ ０．０５）；Ⅲ波潜伏期也延长，较对照组有显著差异（Ｐ＜ ０．０５），同时ＯＰＣＡ与ＳＤＳ的脑干传导时间Ⅰ～Ⅴ峰间潜伏期分别为４．９０±０．９２ ｍ ｓ及４．８９±０．９１ ｍ ｓ，与对照组（４．１９±０．３６ ｍ ｓ）有显著性差异（Ｐ＜ ０．０１）；ＯＰＣＡ与ＳＤＳ相比无差异（Ｐ＞ ０．０５）。Objective:To evaluate the influence of multiple system atrophy (MSA) on the function of brainstem.Methods:The brainstem auditory evoked potentials(BAEP) were recorded in 29 cases of OPCA,10 cases of SDS and 19 healthy volunteers by using Nicolet Viking Ⅱ.Results:Ⅰ-Ⅴ waves were disappeared partially and component Ⅴ in OPCA and SDS were 6.50±0.90 ms and 6.44± 0.79 ms in latencies respectively,which were delayed compared with control( P <0.05).Meanwhile,the brainstem conduction times interpeak intervals Ⅰ-Ⅴ were 4.90±0.92 ms and 4.89±0.91 ms respectively,which were obviously increased compared with control( P <0.01).Conclusion:There were disorders of brainstem conduction time in MSA.

关 键 词：橄榄体桥脑小脑萎缩 诱发电位 听觉 脑干 

分 类 号：R742[医药卫生—神经病学与精神病学]