人工肝支持系统治疗重症黄疸型肝炎的临床观察  被引量:2

Clinical observation of patients with jaundice hepatitis treated by artificial liver support system

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作  者:王宝华 宋树芬 陈美珠 

机构地区:[1]山东省青岛第六人民医院血液净化中心,青岛266033

出  处:《中国血液净化》2003年第12期662-664,共3页Chinese Journal of Blood Purification

摘  要:目的 探讨应用人工肝支持系统对 (ALSS)黄疸型肝炎的临床疗效及安全性。方法 治疗组 72例共行人工肝治疗 2 2 1次 ,平均 3 .2次 ,比较治疗前后临床表现。主要实验室检查指标及人工肝的不良反应。设同期住院病情相似的病例 56例为对照组。结果 治疗组症状明显好转 ;血TBIL、ALT、AST、NH3 、TBA、GGT明显下降 ,PTA、ALB升高 ;治愈好转率 88.89% ,不良反应率 16.7%。对照组治愈好转率 60 .71%。治愈好转病例住院时间 :治疗组 (2 7.16± 2 0 .3 6)天 ,对照组 (58.15± 2 5.49)天 ,两组比较有显著差异。Objective To investigate the clinical effects and s afety of artificial liver support system (ALSS) in patients with jaundice hepati tis. Methods Seventy-two patients were treated with ALSS for 221 time s, and 3.2 times on average. Compared the clinical manifestation, the main labo ratory examination and the adverse reactions of the treatment. Fifty-six similar patients who were admitted to the hospital durtry the same time were as control .Results The patients undergoing artificial liver treatment showe d significant improvements in clinical symptoms; TBIL, ALT, AST, NH 3, TBA, and GGT reduced and PTA, ALB imcreased significantly. The incidence of adverse rea ction was 16.7%, 88.89% of pationts in therapy group were cured or improved and 60.71% in the control group. The average duration of hospitalization:in (27.16± 20.36) d treatment group, and (58.15±25.49) d normal control, there is a signi ficant difference between the two groups. Conclusions ALSS can provide patients with comparatively secure and effective treatment for patients with jaundice hepatitis.

关 键 词:人工肝支持系统 治疗 重症黄疸型肝炎 ALSS 不良反应 

分 类 号:R575.1[医药卫生—消化系统]

 

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