SERUM APOLIPOPROTEIN LEVELS OF PSORIATIC PATIENTS WITH NORMAL SERUM LIPID LEVELS  

作　　者：肖汀 杨次颖 肖毅 宋芳吉 

出　　处：《Chinese Medical Sciences Journal》1997年第4期224-228,共5页中国医学科学杂志（英文版）

摘　　要：Objective’ Recent studies indicated that incidence of occlusive cardiovascular diseases increased in psoriasis. Changes of serum lipid metabolism may be the cause. Apolipoproteinsplay a central role in lipoprotein metabolism in serum. The measurement of serum apo levelsmay reveal the characteristics of lipoprotein metabolism in serum in patients with psoriasisand may help to find an answer to the cause of the high incidence of occlusive cardiovasculardiseases in psoriasis.Method. The apo levels of 31 patients with psoriasis vulgaris and 31 sex- and age-matched healthy individuals with normal serum lipid levels were measured by radial immuno-diffusion assay.Results’ The apo C Ⅲ (t= 2.44,P<0. 05) and apo E (t=2. 12, P<0. 05) of psoriat-ic group elevated significantly- The apo C Ⅲ(t= 2.77, P<0.01) of patients less than 40-year-old and apoE (t= 2. 91, P<0. 01) of male patients eIevated significantly. Conclusha. Abndrmal metabolism of lipoprotein in serum exist in psoriasis, especially inmale patients and/or patients less than 40 years old.

关 键 词：psoriasis vulgaris APOLIPOPROTEINS radial immunodiffusion assay 

分 类 号：R758.63[医药卫生—皮肤病学与性病学]