天津地区肺癌危险因素研究  

Risk factors of lung cancer in Tianjin

作　　者：陈可欣[1] 徐卫历[2] 贾真琳[2] 于满[2] 王庆生[1] 董淑芬[1] 王继芳[1] 

机构地区：[1]天津医科大学附属肿瘤医院,300060 [2]天津医科大学公共卫生学院

出　　处：《中华肿瘤杂志》2003年第6期575-577,共3页Chinese Journal of Oncology

基　　金：国家重点科技攻关项目(编号9690 6 0 1 0 1)

摘　　要：目的　探讨天津地区肺癌危险因素 ,进一步为肺癌危险因素的监测提供依据。方法采用病例 对照研究方法 ,调查年龄在 3 0～ 75岁之间的、原发性肺癌患者 193例和正常对照组 2 59例 ,内容包括一般情况、生活居住环境、生活习惯、既往病史和家族病史等。通过非条件logistic回归模型进行单因素和多因素分析。结果　单因素分析显示 ,吸烟、被动吸烟、饮酒和恶性肿瘤家族史、职业均与肺癌有关。多因素分析结果显示 ,影响肺癌发病的主要因素为吸烟、被动吸烟、10年前月人均收入、10年前人均住房面积和体质指数 (OR分别为 3 .3 0 2 ,1.193 ,1.0 0 3 ,1.0 67和 0 .913 )。结论　吸烟和被动吸烟为肺癌的独立危险因素 ;随着 10年前月人均收入和 10年前人均住房面积的增加 ,肺癌发生的危险性增大 ;Objective To investigate the risk factors of lung cancer in Tian jin and to provide evidence for further monitor there of. Methods A case-control study involving interviews with 193 new cases and 259 controls a g ed 30-76 years was carried out. Structured questionnaires were used to collect i nformation on general condition, living environment, living style, disease and f amily history, etc. Logistic regression model univariate and multivariate analys is were used to pick out the significant lung cancer risk factors. Results By monovariate analysis, risk factors such as smoking, passive smoking, drink ing, history of malignancy in family and occupation were found. By multivariate analysis, smoking, passive smoking, higher body mass index (BMI) and average inc ome and living space per capita ten years earlier were ascertained, t heir operations research (OR) values were 3.302, 1.193, 1.003, 1.067 and 0.9 13. Conclusion Smoking and passive smoking are independent risk factors of lung cancer. Monthly income per person and living space per person 10 years earlier are associated with ele vated risk of lung cancer. Higher body mass index has protective effects on lung cancer risk.

关 键 词：天津市 肺癌 危险因素 流行病学 

分 类 号：R734.2[医药卫生—肿瘤]