用固体碱催化Michael加成反应的研究  

Michael addition reaction catalyzed by solid base

作　　者：徐景士[1] 王红明[1] 陈慧宗[1] 

机构地区：[1]江西师范大学化学学院,江西南昌330027

出　　处：《化学研究与应用》2003年第6期847-848,共2页Chemical Research and Application

基　　金：江西省自然科学基金资助项目(9920009)

摘　　要：Different Michael addition reactions catalyzed by solid base K2O/γ-Al2O3 and KF/γ-Al2O3,MgO/γ-Al2O3 prepared by microwave irradiation method were reported in this paper.For the K2O/γ-Al2O3,not only good yield was attained but also made the reaction of Acetonitrile that usually is regarded as inactive carbonion and α,β-unsaturated compound to carry out.The yield of Michael reaction of Ethyl acetoacetate and Crotonaldehyde catalyzed by KF/γ-Al2O3,MgO/γ-Al2O3,MgO/NaY all could reach to 80% and the latter could reach to 90%.At the same time,the catalysts of different content（the ratio of load）of MgO were also applied in this reaction,and it was found that the best content of MgO was 20%～25%.Different Michael addition reactions catalyzed by solid base K_2O/γ-Al_2O_3 and KF/γ-Al_2O_3,MgO/γ-Al_2O_3 prepared by microwave irradiation method were reported in this paper.For the K_2O/γ-Al_2O_3,not only good yield was attained but also made the reaction of Acetonitrile that usually is regarded as inactive carbonion and α,β-unsaturated compound to carry out.The yield of Michael reaction of Ethyl acetoacetate and Crotonaldehyde catalyzed by KF/γ-Al_2O_3,MgO/γ-Al_2O_3,MgO/NaY all could reach to 80% and the latter could reach to 90%.At the same time,the catalysts of different content(the ratio of load)of MgO were also applied in this reaction,and it was found that the best content of MgO was 20%～25%.

关 键 词：固体碱 催化剂 MICHAEL反应 加成反应 反应时间 

分 类 号：O621.256.7[理学—有机化学]