腮腺癌术后放射治疗的临床分析  

Clincal Analysis of Postoperative Radiotherapy in 25 Patients with Parotid Gland Carcinoma

作　　者：张俊红[1] 梁辰[1] 王涛[1] 谢丛华[1] 

机构地区：[1]武汉大学中南医院肿瘤放化疗科,武汉430071

出　　处：《武汉大学学报（医学版）》2004年第1期89-90,共2页Medical Journal of Wuhan University

摘　　要：目的 :回顾分析腮腺癌术后放射治疗的作用及其预后因素。方法 :1 991年 1月～ 1 994年 1 2月 ,2 5例经病理证实的腮腺癌 (Ⅰ期 2例 ,Ⅱ期 5例 ,Ⅲ期 1 2例 ,Ⅳ期 6例 )术后采用60 Coγ线和 1 80kVX线或直线加速器电子束进行放射治疗 ,并随防 5年以上。结果 :全组 5年生存率为 72 % ,5年局部控制率为 88.0 %。术后放疗以 5 0～ 6 0Gy剂量组疗效好 ,5年生存率为 85 .7%。低分化腺癌及未分化癌预后较差。结论 :腮腺癌应提倡手术加放射的综合治疗 ,采用光子束和电子束混合线照射 ,肿瘤剂量予 5 0～ 6 0Gy为宜。Objectice: To analyse the role of postoperative radiotherapy for parotid gland carcinoma and the prognostic factors retrospectively. Methods: From Nov.1991 to Aug.1994,25 postoperated patients with parotid gland carcinoma(2 in stage Ⅰ,5 in stage Ⅱ,12 in stage Ⅲ,6 in stage Ⅳ)were radiated by 60 Co γ rays and linear accelerator E rays. All patients were diagnosed by pathology and followed up for more than 5 years. Results: The average 5 year survival rate and local control rate for all patients were 72.0% and 88.0%respectively. The group given dose 50～60 Gy had better prognosis and their average 5 year survival rate was 85.7%. Poor prognosis was observed in the cases with the low differentiated adenocarcinoma and undifferentiated carcinoma. Conclusion: It is recommended that treatment for parotid gland carcinoma should combined surgery with radiation. The patients who were given dose 50～60 Gy by the mixed photon electron beam can get better prognosis. Clinical stage and pathological type was the important prognostic factor.

关 键 词：腮腺肿瘤 放射治疗 预后 腮腺癌 术后 临床分析 病理类型 

分 类 号：R739.8[医药卫生—肿瘤] R730.55[医药卫生—临床医学]