胆囊癌及胆囊腺瘤中p53蛋白异常表达的研究  

作　　者：梁喜林[1] 尹继云[1] 赵红[1] 

机构地区：[1]中国·武警河南总队医院450052

出　　处：《美国中华健康卫生杂志》2003年第3期14-15,共2页

摘　　要：Objective To inviestigate the expression of gall bladder cancer and its relationship with eaneeration. Methods Immunohistoehemistry techniques are used to detect the expression of p53 protein in 36 eases of gall bladder cancer and 23 adenoma. Results p53 protein were founded positive in 19 cases (52.78%) of gall blodder cancer, in 5 cases (21.74%) of adenoma. Conclusion There is close relationship between the over expression and the cancemtion of gall bladder, p53 gene mutation and over expression are in the early stage of gall bladder cancer, and play an important role in the cancemtion of adenoma.

关 键 词：胆囊癌 胆囊腺瘤 P53蛋白 P53基因 肿瘤 

分 类 号：R735.8[医药卫生—肿瘤]