Barrett食管与幽门螺杆菌感染关系的研究  

LINK OF BARRETT′S ESOPHAGUS AND HELICOBACTER PYLORI INFECTION

作　　者：董来华[1] 陈龙根[1] 王维武[1] 

机构地区：[1]绍兴文理学院医学院附属医院,浙江绍兴312000

出　　处：《医师进修杂志》2003年第12期24-25,共2页Journal of Postgraduates of Medicine

摘　　要：目的　探讨Barrett食管 (BE)与幽门螺杆菌 (Hp)感染的关系。方法　经胃镜及组织学检查 ,选取BE患者 3 2例作为研究组 ,单纯反流性食管炎 (RE)及正常人各 3 0例作为对照组 ,比较组间Hp感染情况及前两组Hp感染与炎症分级间的关系。结果　在食管部位 ,Hp阳性率研究组明显高于两对照组 (P <0 .0 1) ;在胃窦部 ,Hp阳性率无组间差异 (P >0 .0 5)。在BE组 ,Hp阳性率中、重度炎症均高于轻度炎症 (P <0 .0 5)。在RE组 ,Hp阳性率在轻、中、重度炎症间无差异 (P >0 .0 5)。结论　Hp感染是引起BE的重要原因之一并可能与其炎症轻重相关 。Objective\ To investigate the association between Barrett′s esophagus(BE) and helicobacter pylori(Hp). Methods\ Thirty-two BE as study group, 30 reflux eso phagitis(RE)and 30 normal persons as control groups were selected by gastric e ndoscopies and historical methods and Hp infection status and i nflammation-grades of them were compared each other. Results\ Hp esophageal infe ctious rate in study group(46.9%)was significantly higher than two control gro ups(P<0.01),but no significant differentiations between study group (50%)and other two groups in stomach(P>0.05). The moderate and severe grade esophagitis have higher Hp esophageal infectious rates than mild ones but no significant differentiations in stomach. Conclusion\ Hp infection m ay play an important role in BE occurring and its inflammation grades, moreover, Hp induced BE may not be associated with esophageal reflux.

关 键 词：BARRETT食管 幽门螺杆菌 反流性食管炎 病毒感染 

分 类 号：R571[医药卫生—消化系统]