血管性痴呆患者脑白质病变的MRI研究  

MRI Study on White Matter Lesions in Patients with Vascular Dementia

作　　者：陈希颖[1] 廉宗澂[1] 

机构地区：[1]天津医科大学第二医院,天津300211

出　　处：《医学临床研究》2003年第11期817-819,共3页Journal of Clinical Research

摘　　要：目的探讨血管性痴呆 (vasculardementia ,VD)脑白质病变 (whitematterlesions ,WMLs)MRI半定量测量方法 ,以期为其影像学诊断提供参考指标。方法选择VD和中风后无痴呆 (strokewithoutdementi a ,SWD)患者各 30例。使用Toshiba 1.5TVisart、Signa 1.5TMR扫描仪进行头颅MRI扫描 ,测量WMLs程度。结果VD组WMLs的发生率与SWD组无差异 ,而其中度和重度WMLs的构成比高于SWD组。结论不能以WMLs的出现提示有认知功能下降 ,然而中、重度WMLs与认知功能损害相关。ObjectivesTo investigate the techniques of measurement for semi-quantitating the white matter lesions (WMLs) of vascular dementia(VD) displayed on MRI, with aim at providing referential markers to its early imaging diagnosis. MethodsEach thirty cases of VD and stroke without dementia(SWD)were selected separately. The cranial MRI was performed on Toshiba 1.5T Visart or Signa 1.5T scanner, and the degree of WMLs was measured.ResultsThere was no significant difference between the incidence of WMLs in VD group versus that in SWD group. But the constituent ratio of moderate to severe WMLs in VD group was higher than that in SWD group.ConclusionThe appearance of WMLs is not an indication of decreased cognitive function. However, mederate and severe WMLs are correlated to the impairment of cognitive function.

关 键 词：血管性痴呆 脑白质病变 MRI 磁共振成像 认知功能损害 

分 类 号：R749.13[医药卫生—神经病学与精神病学] R445.2[医药卫生—临床医学]