子宫内膜间质肉瘤19例临床病理分析  

Endometrial Stromal Sarcoma:A Clinicopathologic Study of 19 Cases and Review of the Literature

作　　者：刘杜先[1] 刘建华[1] 王强修[2] 

机构地区：[1]新泰市人民医院病理科,山东新泰271200 [2]山东省立医院病理科,山东济南250021

出　　处：《河南肿瘤学杂志》2003年第6期430-432,共3页Henan Journal of Oncology

摘　　要：目的　探讨子宫内膜间质肉瘤 (ESS)的临床病理特征及激素受体表达情况。方法　对 19例病例进行总结分析并做免疫组化染色。结果　ESS多见于 3 0～ 5 0岁青壮年 ;判断ESS的恶性度主要依据肿瘤累及范围及瘤细胞异型性 ,核分裂计数起参考作用 ;免疫组化证实瘤细胞具有多潜能性分化且雌、孕激素受体表达率较高。结论　ESS的恶性度要严格按照标准区分 ,ESS内分泌治疗效果较好 ,前景令人鼓舞。Objective To investigate the clinic-pathological features and oestrogen receptor expression level of endometrial stromal sarcoma.Methods 19 cases were observed with histologic and immunohistochemical techniques.Results The lesion usually occurred in young adults (30～50 years old).The malignant degree of tumors based on aggressive extention and cytologic atypia.Amount of mitotic count is a referential help for the diagnosis of ESS.Immunohistochemical staining shows ESS arises from primitive pluripotential cells capable of differentiating into many cell types.Expression level of oestrogen receptor(ER) and progesterone receptor(PR) is high.Conclusions To judge the malignant degree of ESS should be based on standard strictly.Endocrine treatment is available.

关 键 词：子宫内膜间质肉瘤 病理特征 激素受体 免疫组化染色 临床特点 鉴别诊断 

分 类 号：R737.33[医药卫生—肿瘤]