宫颈细胞学检查及人乳头瘤病毒检测对诊断宫颈病变的作用  

Effect of cervical cytology detection and human papilloma virus detection for the diagnosis of cervical lesions

作　　者：邢会美[1] 张淑惠[1] 

机构地区：[1]北京市朝阳区妇幼保健院,100026

出　　处：《中国社区医师》2015年第6期107-108,共2页Chinese Community Doctors

摘　　要：目的:比较单纯宫颈细胞学检查与宫颈细胞学检查联合人乳头瘤病毒筛查检出宫颈高级别病变的优势,比较人乳头瘤病毒单一高危亚型感染与多重高危亚型感染致病风险。方法:2009年7月-2011年5月收治女性患者230例,对宫颈细胞学检查、人乳头瘤病毒检测及活检病理诊断结果进行分析。结果:活检病理诊断证实宫颈细胞学检查ASCUS以上病变合并HPV高危型感染宫颈高级别病变检出率43.1%。宫颈细胞学正常而单纯HPV高位型感染宫颈高级别病变检出率24.6%。宫颈细胞学检查ASCUS以上病变而同时HPV无感染或仅低危型感染宫颈高级别病变检出率19.0%。HPV单一高危亚型感染与≥2种多重高危亚型感染致病风险差异无统计学意义。结论:TCT联合HPV筛查宫颈病变优于单纯TCT筛查。HPV单一高危亚型感染与多重高危亚型感染致病风险相同。Objective:To compare the advantages of simple cervical cytology detection and cervical cytology combined human papilloma virus detection for screening high-level cervical pathological changes and compare the risks of treating diseases of single high-risk human papilloma virus subtype infection and multiple high-risk subtype infection.Method:The means of cervical cytology and HPV detection and biopsy pathologic diagnosis of 230 women from July 2009 to May 2011 were analyzed.Results:The pathology diagnosis confirmed that the high-level cervix lesion detection rate was 43.1% with above ASCUS lesions by cervical cytology and high risk type HPV infection.The high-level cervix lesion detection rate was 24.6% with normal cervical cytology and HPV type high infection.The high-level cervix lesion detection rate was 19.0% with above ASCUS lesions by cervical cytology and no infection or only low-risk HPV infection.There was no significant difference of risk for treatment between single high-risk HPV subtype infection and a minimum of 2 kinds of multiple high-risk subtype infection.Conclusion:TCT joint HPV screening cervical lesion was better than that of single TCT screening.The risk for treatment were the same between single high-risk HPV subtype infection and multiple high-risk subtype infection.

关 键 词：宫颈细胞学 人乳头瘤病毒 单一高危亚型感染 多重高危亚型感染 宫颈病变 

分 类 号：R737.33[医药卫生—肿瘤]