单纯性肥胖儿童能量代谢的研究  

STUDY ON ENERGY METABOLISM IN SIMP LE OBESE CHILDREN

作　　者：张彩霞[1] 蒋卓勤[1] 

机构地区：[1]中山大学公共卫生学院医学营养学系,广州510080

出　　处：《营养学报》2003年第4期357-361,共5页Acta Nutrimenta Sinica

基　　金：广东省卫生厅基金项目 ( No.A1 9981 2 0 )

摘　　要：目的 :　通过对单纯性肥胖儿童的能量代谢研究 ,了解肥胖状态下儿童能量代谢的变化 ,为进一步研究儿童肥胖的发病机制及防治措施提供依据。方法 :　对筛选出来的 54名肥胖儿童和 60名正常体重儿童进行基础代谢、休息代谢、标准化骑车试验以及能量摄入量和全日总能量消耗的测定。结果 :　基础代谢、休息代谢和标准化骑车试验能量消耗以 k J/ h表示 ,肥胖组儿童显著高于非肥胖组 (P<0 .0 5)。肥胖组儿童的全日能量摄入量、全日总能量消耗量均显著高于非肥胖组儿童 ,(P<0 .0 5)。肥胖组儿童中体力活动时间和重体力活动时间显著低于非肥胖组儿童 (P<0 .0 5) ,而轻体力活动时间和睡眠时间显著高于非肥胖组儿童 (P<0 .0 5)。基础代谢与去脂组织(FFM)呈显著正相关 ,用 FFM校正以后 ,基础代谢的能量消耗肥胖组儿童仍然高于非肥胖组儿童。结论 :　本研究观察的肥胖儿童并不存在能量代谢方面的缺陷使其发生肥胖的易感性增高。儿童肥胖 ,可能与其进食过多 ,加之每日运动量不足以及从事中体力活动。Objective: The energy intake and energy expenditure were measured in order to observe the variation of energy metabolism in simple obese children and provide evidences for further research of etiology, prevention and control of obesity in children. Methods: Basic metabolic rate(BMR), resting metabolic rate (RMR) and energy expenditure of standardized cycling were measured by using open-circuit indirect calorimetry in 54 obese children and 60 nonobese children in a full-time boarding school in Guangzhou suburb. Total energy expenditure (TEE) was estimated by time record of activities and factorial approach. Dietary intake was surveyed by weighing method. Results: When expressed as kJ/h, BMR,RMR, energy expenditure of standardized cycling were significantly higher(P<0.05) in obese children than in nonobese ones. Energy intake and TEE were also significantly higher(P<0.05) in obese children than in nonobese ones.Time spent in moderate and heavy physical activity was significantly less(P<0.05)in obese than in nonobese children, whereas time for light physical activity and sleeping was significantly more(P<0.05). BMR was positively correlated with fat free mass(FFM).BMR adjusted for FFM was still significantly higher in the obese children. Conclusion: The cause of children's obesity may be related with their more intake, less exercise and time spent in moderate and heavy physical activity.

关 键 词：单纯性肥胖 儿童 能量代谢 发病机制 防治 

分 类 号：R723.14[医药卫生—儿科]