探测前哨淋巴结在早期宫颈癌中的应用  

Preliminary application of the sentinel lymph node detection in early cervical cancer

作　　者：刘琳[1] 章文华[2] 李斌[2] 

机构地区：[1]中国医学科学院中国协和医科大学肿瘤医院核医学科,北京100021 [2]中国医学科学院中国协和医科大学肿瘤医院妇瘤科,北京100021

出　　处：《中国癌症杂志》2003年第6期508-510,共3页China Oncology

摘　　要：目的 :评价核素淋巴显像和r探针定位在宫颈癌中确定SLN的应用价值。方法 :2 2例女性宫颈癌病人 ,体检盆腔未扪及肿块。应用99mTc DX 74MBq(2mCi)在宫颈肿瘤周围 2°或 10°处注射 ,行核素淋巴显像后 ,对手术后的标本用γ探针行体外定位 ,并与病理的结果加以对照。结果 :2 2例病人中活检SLN 17例 ,其灵敏度为10 0 % (4/4例 ) ,特异性 10 0 % (13/13例 )。结论 :盆腔前哨淋巴结的病理结果基本能准确反映盆腔淋巴结的病理状态 ,核素定位法在宫颈癌中检测盆腔前哨淋巴结是切实可行和可能的。Purpose:To assess the value of the sentinel lymph node by lymphoscintigraphy and gamma detector probe in early cervical cancer.Methods:22 patients with operable invasive early cervical cancer and clinically proven negative pelvic lymph nodes were included in the study. The 99m Tc-dextran ( 99m Tc-DX) of 74 MBq(2 mCi) was injected into the cervix at 2° and 10°. Lymphoscintigraphy and gamma probe detectors were used to detect the SLN. Results:The SLN was identified in 17 of the 22 patients. The sensitivity and the specificity of the SLN detection to predict the metastasis of the pelvic lymph node was 100% and 100% respectively. Conclusions:Identification of sentinel nodes using radionuclide is feasible and possible in women with early cervical cancer.

关 键 词：宫颈癌 盆腔 前哨淋巴结 核素淋巴显像 Γ探针 

分 类 号：R737.33[医药卫生—肿瘤]