胃癌MCD/MVD双标记检测及其意义  

MCD/MVD were inspected with immunohistochemical double labeled and quantitative analysis in the gastric carcinoma and its significance

作　　者：魏爱君[1] 张友元[1] 熊密[2] 黄望珍[1] 顾磊[1] 

机构地区：[1]湖北省黄石市中心医院,435000 [2]华中科技大学同济医学院病理学教研室

出　　处：《肿瘤防治研究》2004年第1期17-18,共2页Cancer Research on Prevention and Treatment

基　　金：湖北省科技厅重点发展计划资助项目(2 0 0 0 2B2 1)

摘　　要：目的　探讨MCD、MVD与胃癌的关系。方法　免疫组化双标记检测 10 0例胃癌组织中MCD/MVD ,并作定量分析。结果　MCD/MVD≤ 0 .9时 ,癌累及浆膜病例较多 ;MCD/MVD >0 .9时 ,癌累及浆膜病例较少 ,两者比较 ,P <0 .0 5。结论　MCD/MVD的比值与癌浸润深度相关 ,是反映胃癌生物学行为的一个有用指标。Objective To probe into the relationship of mast cell density(MCD), microvessel density(MVD) and gastric carcinoma. Methods Immunohistochemical double labeled method was used for the observation of MCD/MVD in 100 cases of the gastric carcinoma and quantitative analysis. Results Patients of serosa with carcinoma of MCD/MVD ≤ 0.9 were more than of MCD/MVD> 0.9 , P < 0.05 . Conclusion A ratio of MCD/MVD was related to invasion depth of carcinoma, which was a useful index of reflecting on biological feature of the gastric carcinoma.

关 键 词：胃癌 MCD MVD 检测 免疫组织化学 双标记 肥大细胞 微血管 

分 类 号：R735.2[医药卫生—肿瘤] R730.43[医药卫生—临床医学]