直肠癌术前动脉灌注化疗的近期疗效  

RECENT CURATIVE EFFECTS OF PREOPERATIVE TRANSCATHETER ARTERIAL CHEMOTHERAPY IN ADVANCED RECTAL CANCER

作　　者：华长江[1] 殷广福[1] 卢秀仙[1] 许正昌[1] 奚小风[1] 孙伟力[1] 

机构地区：[1]解放军第81医院,南京210002

出　　处：《临床肿瘤学杂志》1996年第3期10-12,共3页Chinese Clinical Oncology

摘　　要：应用Seldinger法对14例中晚期直肠癌行术前动脉灌注化疗(PTAC)。经肠系膜下动脉和/或髂内动脉,选择MMC、DDP、5-FU进行三药配伍,PTAC进行1～4次。化疗后肿瘤有不同程度的缩小,活动度增大,临床症状明显改善,提高了中晚期直肠癌的手术切除率。化疗的大体有效率92.9％,病理组织学有效率78.58％;手术发现淋巴结转移率为21.4％,有效延长了晚期患者的生存时间。Preoperative transcatheter arterial chemotherapy (PTAC) was used with the method of Seldinger in 14 cases of advanced rectal cancer. Pathes of TAC were the inferior mesenteric artery or/and the internal iliac artery. PTAC was done 1 to 4 times for each case with a intermission of 20 to 30 days. After PTAC, the size of tumor was decreased in different degree with increasing of mobility. In 14 cases,the macroscopic efficiency of PTAC was 92. 9% , and the histopathological efficiency was 78. 5%, the rate of lymph node involved was 21. 4%. The result showed that PTAC obviously improved the patient's symptom and increased the rate of resection with efficiently delay of survival time of the patients.

关 键 词：直肠癌 手术 动脉灌注 化疗 病理学 肿瘤 

分 类 号：R735.3[医药卫生—肿瘤] R453[医药卫生—临床医学]