彩超引导门静脉化疗结合瘤内无水酒精注射在中晚期肝癌中的临床应用  

CLINICAL APPLICATION OF SPVC WITH PEIT GUIDEDBY COLOR DOPPLER ULTRASOUND IN THEADVANCED HEPATIC CANCER

作　　者：房秀霞[1] 姚志清[1] 哈斯[1] 郭秀兰[1] 

机构地区：[1]内蒙古医学院第一附属医院,内蒙古呼和浩特010050

出　　处：《内蒙古医学院学报》2003年第4期234-237,共4页Acta Academiae Medicinae Neimongol

基　　金：内蒙古自然科学基金项目 ( 2 0 0 1 0 90 6-1 1 )

摘　　要：目的 :探讨彩超引导下经皮经肝选择性门静脉化疗 ( SPVC)结合瘤内无水酒精注射疗法 ( PEIT)联合肝动脉栓塞化疗 ( TACE)治疗中晚期肝癌的临床应用价值。方法 :2 8例不能手术的中晚期肝癌 ,在 TACE基础上 ,行彩超引导下作 SPVC结合 PEIT。观察治疗前后肿瘤大小 ,血供变化 ,声像图改变及甲胎蛋白 ( AFP)的变化与临床疗效的关系。结果 :肿瘤血供消失和减少率 92 .9% ,肿瘤缩小率 89.3 % ,AFP转阴率 60 .7% ,门静脉癌栓消失和减少率 68.7%。结论 :彩超引导下选择性门静脉化疗结合瘤内无水酒精注射联合 TACE对预防肝癌转移 ,延迟复发 ,及改善预后有肯定意义 ,明显延长病人带瘤生存期和提高了生活质量。objective: To evaluate the clinical significance of selective portal vein chemotherapy (SPVC) and percutaneous ethanol injection therapy (PEIT) guided by color Doppler ultrasonography (CDU) after transhepatic arterial chemo-embolization (TACE). Methods: Twenty eight cases of unresectable middle and advanced stage hepatic carcinoma were treated by SPVC and PEIT after TACE under the guidance of CDU and observed the changes of blood supply and size of tumor, the sonographic characteristics and the clinical effect before and after treatments. Results: The rate of disappearing and reducing of blood supply was 92.9%, the tumor mass shrinkage rate was 89.3%, and AFP negative reversion rate reached 60.7%, the rate of disappearing and reducing of portal vein tumor thrombosis was 68.7%. Conclusion: Ultrasound-guided SPVC and PEIT after TACE has positive significance for preventing from recurrence and improving prognosis, obviously prolonging survival time and improving survival quality.

关 键 词：原发性肝癌 选择性门静脉化疗 瘤内无水酒精注射疗法 肝动脉栓塞化疗 介入治疗 介入超声 

分 类 号：R735.7[医药卫生—肿瘤]