长甲牌百消丹辐射灭菌剂量设定的研究  

STUDY ON DETERMINATION OF RADIATION DOSE FOR STERILIZATION OF CHANG-JIA BRAND BAI-XIAO DAN

作　　者：程海霞[1] 刘清芳[1] 张同成[1] 

机构地区：[1]苏州大学放射医学与公共卫生学院,苏州215007

出　　处：《中国消毒学杂志》2003年第4期247-249,共3页Chinese Journal of Disinfection

摘　　要：采用活菌计数法和D_(10)值测定对长甲牌百消丹辐射灭菌剂量进行设定。结果,3批长甲牌百消丹初始染菌数平均值分别为2620 cfu/g、15630 cfu/g和4900 cfu/g,3批平均总菌数为7717 cfu/g,污染菌数范围为1700～28000 cfu/g。测得D_(10)值为1.75kGy,计算出最低灭菌剂量为17.70kGy。结论,^(60)钴辐照对长甲牌百消丹辐射灭菌剂量为17.70 kGy,确定灭菌保证水平为10^(-3)。Viable bacteria count method and measurement of D10 value were used to determine the radia-tion dose for sterilization of Chang-Jia Brand Bai-Xiao Dan (Pill). The results showed that the average ini-tial bacterial count of 3 batches of Chang-Jia Brand Bai-Xiao Dan was 2 620 cfu/ g, 15 630 cfu/ g and 4 900 cfu / g respectively, with the average total bacterial count of the 3 batches being 7 717 cfu/ g and the range of contaminating bacteria count being 1700- 28000 cfu/ g. The D10 value was measured to be 1.75 kGy and the minimum bactericidal dose was calculated to be 17.70 kGy. Conclusion: the 60Co radiation dose for sterilization of Chang-Jia Brand Bai-Xiao Dan is 17.70 kGy and the assured sterilization level is

关 键 词：辐照灭菌 初始污染菌 D10值 百消丹 

分 类 号：R187.1[医药卫生—流行病学]