彩色多普勒检测动脉瘤血流动力学的实验研究  

Hemodynamics in Experimental Canine Carotid Aneurysms:Color Doppler Flow Imaging analysis

作　　者：华秀蓉[1] 李文彬[1] 沈天真[1] 陈星荣[1] 

机构地区：[1]上海医科大学华山医院超声室,上海医科大学华山医院放射科

出　　处：《中国医学计算机成像杂志》1995年第1期58-60,共3页Chinese Computed Medical Imaging

摘　　要：目的：探讨动脉瘤的血流动力学及其与动脉瘤发展之间可能的相互关系。材料和方法：用静脉囊镶嵌法将１８条犬制成三种类型（单侧型、分叉型、末梢型）颈总动脉瘤模型，术后２周、４周分别用彩色多普勒（ＡＴＬＵｌｔｒａｍａｒｋ９型）检测载瘤动脉、动脉瘤的血流方向、状态，及其血流参数（ＭａｘＶ、ＭｉｎＶ、ＴＡＶ、ＰＩ、ＲＩ值），进行方差分析和配对ｔ检验。结果：彩色多普勒可发现动脉瘤颈部的ＭａｘＶ、ＭｉｎＶ、ＴＡＶ值低于载瘤动脉主干，但ＲＩ、ＰＩ值较之增高；动脉瘤的远侧缘、底部、近侧缘呈红色的层流，瘤中央呈红、兰相镶的湍流；动脉瘤颈部、远侧缘、底部、近侧缘的ＭａｘＶ、ＭｉｎＶ、ＴＡＶ值４周低于２周，ＲＩ值却增高，并二者比较，差异有非常显著性（Ｐ＜０．００１）。结论：彩色多普勒检测实验性动脉瘤有利于了解动脉瘤发展、血栓形成或破裂的血流动力学。Purpose :To study the probable relationship between the hemodynamics and the development of aneurysm by Color Doppler flow imaging. Materials and Methods:The common carotid aneurysm formats were made in 18 canine by venous bulbar wedging method,dividing into 3 types(Unilateral 6,bifurcation 6,and terminal 6),2 weeks and 4 weeks postoperative follow up by Color Doppler (ATL Ultramark 9 Type) were evaluated respectively in displaying the parentartery, the hemodynamics and flow parameter of the aneurysms(Max V、 Min V、 TAV、 PI、 RI Value) and finally completed with analysis and conjugation tests. Results: Color Doppler could discovered the Max V、Min V、TAV at the neck of the aneurysm were lower than those of the parent artery but somewhat higher in Rl and PI values, the distal border, fundus and proximal border presented as red colored layerings while the central part of the aneurysm showing red and blue partition turbulents. The Max V、Min V、TAV of the neck, distal border, fundus and proximal border were lower at 4 week than those of 2 weeks postoperatively but higher in RI valus with obvious disparity (P<0.001).Conclusion: Color Doppler flow imaging of the experimental canine aneurysms gave a prospective evaluation on development, thrombus formation and rupture hemodynamics.

关 键 词：彩色多普勒 动脉瘤 血流动力学 血栓形成 瘤体破裂 动物实验 

分 类 号：R732.21[医药卫生—肿瘤] R730.41[医药卫生—临床医学]