大茴香醛缩邻氨基苯甲酸Schiff碱及其配合物的合成、结构和Cu(Ⅱ)配合物的抑菌活性  

Synthesis, Structure of Schiff Base Condensed from 4-Methoxybenzaldehyde with Anthranilic Acid and Its Complexes and Antibacterial Activities of Cu(Ⅱ) Complex

作　　者：李培凡[1] 刘燕[1] 王智[1] 刘斌[1] 

机构地区：[1]天津医学高等专科学校,天津300052

出　　处：《天津师范大学学报（自然科学版）》2003年第4期13-15,共3页Journal of Tianjin Normal University：Natural Science Edition

基　　金：天津市自然科学基金资助项目(003601711)

摘　　要：合成了大茴香醛缩邻氨基苯甲酸Schiff碱及其过渡金属配合物,利用红外和紫外光谱对其进行了结构表征.结果表明,大茴香醛缩邻氨基苯甲酸Schiff碱为二齿配体,通过亚胺基N原子和羧基O原子可与过渡金属离子形成2∶1型的双六元环配合物.对革兰氏阳性和阴性菌的抑菌实验结果表明,Cu( )配合物具有较高的抑菌活性.The synthesis of Schiff base condensed from 4-methoxybenzaldehyde with anthranilic acid and its complexes are reported and characterized by IR and UV. The structure characterization of the condensed product indicates that it is a neutral didentate ligand in which the imine nitrogen and carboxyl oxygen atoms coordinate with copper(Ⅱ) and form a dihexacyclic compound of n_L∶n_(Cu)=2∶1. The results of antibacterial activities against E.Coli and S.Aureus show that the Cu(Ⅱ) complex have much more activities.

关 键 词：配合物 合成 结构表征 抑菌活性 大茴香醛缩邻氨基苯甲酸Schiff碱 

分 类 号：O625.632[理学—有机化学]