纳米物质在肿瘤光热治疗及药物可控释放中的应用  

Nanoparticles in Photothermal Therapy and Photothermal

作　　者：Guissi Fida 吕丽伟 韩智豪[1] 顾月清[1] 

机构地区：[1]中国药科大学生物医学工程教研室,江苏南京210009

出　　处：《药物生物技术》2015年第6期549-552,共4页Pharmaceutical Biotechnology

摘　　要：光热治疗(PTT)是一种微创治疗方法,通过将光子能量被转换成热能来杀死癌细胞。文章介绍了纳米粒子在肿瘤光热治疗方面的研究现状和光热敏感型药物在体内的释放过程及其产生的局部化疗效果。最后,笔者对光热治疗的未来发展前景和挑战进行了展望。Photo-thermal therapy( PTT) is a minimally-invasive therapy in which photon energy is converted into heat to kill cancer.The current status of the use of nanoparticles for photothermal treatments is reviewed in this mini-review paper with a focus on the photothermal drug release from and localized chemotherapy therapy. The perspectives and challenges in the future development of photothermal therapy will also be discussed.

关 键 词：光热治疗 热敏脂质体 纳米粒子 药物释放 靶向给药 

分 类 号：R730.5[医药卫生—肿瘤]