^(18)F-FDOPA PET显像在脑胶质瘤中的临床应用价值  

Application of ^(18)F-FDOPA PET imaging in gliomas

作　　者：葛璟洁[1] 张政伟[1] 陆秀宏[1] 管一晖[1] 

机构地区：[1]复旦大学附属华山医院PET中心,上海200235

出　　处：《肿瘤影像学》2016年第3期213-216,共4页Oncoradiology

基　　金：国家自然科学基金(No:81271516;81571345);上海市科委科研计划项目(No:16411968700)

摘　　要：脑胶质瘤是发病率最高的神经系统来源肿瘤。目前临床上诊断胶质瘤的方法主要为MRI平扫及增强,但存在一定的局限性。近年来,随着PET与核素显像剂的不断发展和改进,其在胶质瘤领域的研究越来越深入,尤其是18F-FDOPA PET显像在原发性及复发性胶质瘤的诊断、鉴别、分级、定位、治疗和预后评估中具有较高的临床应用价值。本文就此进行综述。Glioma is one of the most common neurologically originated tumor. Although MRI scanning is the major approach to make diagnosis of glioma at present, it still has some limitations. With the development and improvement of positron emission tomography imaging techniques and radionuclide agents, PET imaging such as ^(18)F-FDOPA PET imaging has played a more and more important role in the diagnosis, discrimination, grading, localization and prognosis evaluation of primary and recurrent gliomas. The present paper summarizes the research progress in this field.

关 键 词：胶质瘤 正电子发射断层成像 L-6-18F-氟代多巴 磁共振成像 

分 类 号：R739.41[医药卫生—肿瘤] R730.44[医药卫生—临床医学]