消化道恶性肿瘤手术切除同期大网膜移植胎胸腺临床观察  

Treatment of alimentary canal malignant tumor by transplantation of embryonic thymus in epiploon during resection

作　　者：皇甫超申[1] 王玉兰[1] 马红兵[2] 施巩宁[2] 马传根[2] 

机构地区：[1]河南大学医学院,河南开封475001 [2]河南大学附属淮河医院

出　　处：《山东医药》2003年第36期13-14,共2页Shandong Medical Journal

基　　金：河南省科技攻关资助项目 ( No.0 12 4170 2 2 8)

摘　　要：目的　观察消化道恶性肿瘤手术同期大网膜移植胎胸腺的疗效。方法　在胃、大肠恶性肿瘤手术切除的同时 ,将 16～ 2 4周胎龄水囊引产的胎儿胸腺移植于患者大网膜。术后观察患者临床表现及外周血 T细胞亚群的变化。结果　患者术后临床症状改善明显 ,CD3、CD4 、CD4 /CD8升高 (P均 <0 .0 5 ) ,CD8升高不显著。结论　消化道恶性肿瘤手术后同期大网膜移植胎胸腺不但简便 。Objective To probe into curative effect of alimentary canal malignant tumor by transplantation of embryonic thymus in epiploon during resection.Methods During gastric and colorectal malignant tumor resection,thymus that was harvested from donors of 16～24 weeks stillborn fetus by induced labor with water bag were transplanted into epiploon postoperation.Results Patients clinical conditions were well,CD 3andCD 4 lymphocytes CD 4/CD 8 were significantly higher in the transplantion group(P< 0.05).Conclusion Transplanting embryonic thymus into epiploon during operation not only simple,but also significantly improve immunity of patients.

关 键 词：消化道恶性肿瘤 手术治疗 切除术 同期手术 大网膜胚胎胸腺移植 

分 类 号：R735[医药卫生—肿瘤] R730.56[医药卫生—临床医学]