肛管直肠恶性黑色素瘤  

Primary Malignant Melanoma of the Anorectum

作　　者：吉喆[1] 李玉坤[2] 尉继伟[1] 

机构地区：[1]北京铁路局大同铁路中心医院外科,大同037005 [2]北京解放军总医院普外科,北京100853

出　　处：《中国现代手术学杂志》2003年第3期214-216,共3页Chinese Journal of Modern Operative Surgery

摘　　要：目的　总结肛管直肠恶性黑色素瘤的诊断与治疗经验。　方法　回顾性分析 10例肛管直肠恶性黑色素瘤的临床病例资料。　结果　出现症状至确诊时间平均 8( 2～ 12 )个月 ,首诊确诊 4例 ,误诊 6例。手术 9例 ,8例肿瘤直径 >3cm。其中 8例行腹会阴联合根治术 ,1例以直肠息肉、肛乳头肥大行局部切除 ,1例放弃手术仅行化疗 ,3月后死于肝、肺腹股沟等广泛转移。术后 8例行化疗 ,2例辅助放疗 ,化放疗联合应用 1例。术后 2年内死亡 5例 ,余 4例存活 ,存活最长者已超过 6年。　结论　肛管直肠恶性黑色素瘤恶性程度高 ,早期行腹会阴联合根治术是最优选择。Objective To summarize the diagnosis and treatment of the primary malignant melanoma of the anorectum. Methods 10 cases of primary malignant melanoma of the anorectum were retrospectively reviewed. Results 10 cases were accurately diagnosed in average 8(2～12) months after symptoms appeared. 9 cases underwent operations, 1 refused operation, and 1 received local mass resection. 8 cases underwent radical abdominoperineal resection. Among them 6 died in two years, 4 have survived, the longest has lived for more than 6 years. Conclusions Radical abdominoperineal resection is the best choice for primary malignant melanoma of the anorectum. Long term survival depends both on earlier diagnosis and the therapeutic approaches.

关 键 词：肛管直肠恶性黑色素瘤 诊断 治疗 手术 化疗 肛门肿瘤 直肠肿瘤 

分 类 号：R735.3[医药卫生—肿瘤] R739.5[医药卫生—临床医学]