老年性黄斑变性脉络膜新生血管与脉络膜分水带  

Relationship between choroidal neovascularization and macular choroidal watershed zones in patients with age-related macular degeneration

作　　者：李亚萍[1] 黎晓新[1] 张晓光[2] 吕永顺[1] 刘国栋[1] 

机构地区：[1]北京大学人民医院眼科,现在吉林大学第二医院眼科100044 [2]吉林大学第二医院眼科

出　　处：《中华眼底病杂志》2003年第2期76-78,共3页Chinese Journal of Ocular Fundus Diseases

摘　　要：目的　观察老年性黄斑变性 ( age- related macular degeneration,AMD)的脉络膜新生血管( choroidal neovascularization,CNV)与黄斑区脉络膜分水带 ( choroidal watershed zones,CWZ)的关系。　方法　对比分析 AMD患者 5 7例 5 7只眼以及与之年龄相匹配的无 AMD的患者 35例 35只眼的吲哚青绿血管造影 ( indocyanine green angiography,ICGA)资料 ,观察 CNV与黄斑区 CWZ的关系。　结果　 5 7只 AMD眼中 ,35只眼有黄斑区 CWZ,占 6 1.4% ;对照组 35只眼中 ,3只眼有黄斑区 CWZ,占 8.5 7% ,两者比较差异有显著性的意义 ( P<0 .0 5 )。在有 CNV的 43只渗出型 AMD眼中 ,32只眼有黄斑区 CWZ,占74.4% ,其中 2 9只眼的 CNV来自黄斑区 CWZ,占 90 .6 %。　结论　黄斑区 CWZ可能是渗出型 AMD的CNV好发部位。ObjectiveTo investigate the possible relationship between choroidal neovascularization (CNV) and macular choroidal watershed zones (CWZ) in patients with age-related macular degeneration (AMD). MethodsFifty-seven selected indocyanine green video angiograms (ICGA) of 57 patients (57 eyes) with AMD were evaluated, and 35 ones of the healthy fellow eyes of 35 patients with unilateral non-AMD fundus diseases were selected as age-matched control. The video angiograms were evaluated for investigating the relationship between CNV and macular CWZ. ResultsIn 57 eyes with AMD, 35 (61.4%) had macular CWZ, while in 35 control patients only 3 (8.57% ) had. The difference was significant (P<0.05). In 43 eyes with exudative AMD and CNV, 32 (74.4%) had macular CWZ, including 29 eyes (90.6%) with CNV caused by macular CWZ. ConclusionMacular CWZ could be a predilection site of CNV in exudative AMD.

关 键 词：老年性黄斑变性 脉络膜 新生血管 脉络膜分水带 吲哚青绿血管造影 

分 类 号：R774.5[医药卫生—眼科]