淋巴结转移阴性胃癌的临床病理特点及预后多因素分析  

The Clinicopathological Characteristics and Multivariate Analysis of Prognosis of Gastric Cancer without Lymph Node Metastasis

作　　者：郭澎涛[1] 徐惠绵[1] 陈峻青[1] 

机构地区：[1]中国医科大学附属第一医院肿瘤科,沈阳市110001

出　　处：《中国肿瘤临床》2003年第7期511-513,共3页Chinese Journal of Clinical Oncology

摘　　要：目的:探讨淋巴结转移阴性胃癌的临床病理特点及其预后因素,为临床治疗提供依据。方法:以本院1980～1990年间施行胃癌根治手术,检取10个以上淋巴结均无转移者104例为研究对象,总结临床病理特点;采用Kaplan-Meier法进行单因素分析,COX比例风险模型进行多因素分析,判定淋巴结转移阴性胃癌的独立预后因素。结果:淋巴结转移阴性胃癌浸润深度较浅,其中近29.8%为早期胃癌(31/104)。5年生存率为76.0%(79/104)。结论:淋巴结转移阴性胃癌施行根治术后预后较好,浸润深度是其独立预后因素。Objective:To investigate the clinicopathological characteristics and assess the prognosis of gastric cancer without lymph node metastasis in order to provide some useful infor-mation on therapy.Methods:In this study,the clinico pathological characteristics of104cases of gastric cancer without lymph node metasta sis,who received radical resection in Department of Oncology of our hospital from1980to1990,were analyzed.At least10lymph nodes were ob-tained per specimen.The Kaplan-Meier procedure and COX proportional hazard model were used in univariate and multivariate analysis respectively to assess the prognosis.Results:Serosa of most cases was not involved and29.8%(31/104)of cases were early gastric cancer.The5-year sur vival rate was76.0%.Conclusions:Patients with gastric cancer without lymph node metastasis may have well prognosis since radical re section was performed.Invasive depth was the indepen-dent prognostic factor.

关 键 词：胃癌 淋巴结转移 根治术 预后 

分 类 号：R735.2[医药卫生—肿瘤]