急性脑血管病应激性高血糖与血清胰岛素及病灶情况的研究  

The relationship between irritable hyperglycemia?serum insulin and nidus circumstance within acute cerebral vascular disease

作　　者：黄丽娜[1] 富奇志[1] 王琳[1] 郎鸿志[1] 魏月芳[1] 

机构地区：[1]河南科技大学第一附属医院神经内科,河南洛阳471003

出　　处：《中风与神经疾病杂志》2003年第3期248-249,共2页Journal of Apoplexy and Nervous Diseases

基　　金：河南省洛阳市科技计划项目(2 0 0 180 62 )

摘　　要：目的　探讨急性脑血管病 (ACVD)应激性高血糖及血清胰岛素与病变性质、大小、部位之间的关系。方法　采用双盲法检测发病 1周内ACVD患者空腹血糖 (FBG)和空腹胰岛素 (FINS)。FBG升高者为高血糖组 ,FBG正常者为正常血糖组 ,每组各 1 0 0例。根据头部CT或MRI记录高血糖组病变的性质、大小及部位。结果　两组FBG与FINS之间呈正相关关系 ;高血糖组血糖升高的水平与病变的性质、大小、部位有关 ;经统计学处理有显著性差异。结论　ACVD应激性高血糖与胰岛素抵抗 (IR)有关 ;脑出血比脑梗死、大病灶比小病灶。Objective To study the relationship between irritable hyperglycemia,serum insulin and quality,position,size of the focuses. Methods Examined the fasting blood glucose (FBG) and the fasting serum insulin(FINS) of patients who had fallen acute cerebral vascular disease(ACVD) in one week though double blindness way. Divided them into two groups,100 cases every group,in which one were those in high FBG,the other were in normal FBG. Recorded niduds quality,nidus position,nidus size of patients with high FBG according to CT and MRI. Results There was positive correlation between FBG and FINS in high blood glucose group. The level of hyperglycemia had markable difference in niduds quality,nidus position and nidus size through stactical management. Conclusion Irritable hyperglycemia of ACVD had correlation with insulin resistance. The increasing level of blood glucose was apparent in intracerebral hemorrhage,large size nidus and which focus near midline of brain compared with ischemia,small size nidus and which focus far away from midline of brain.

关 键 词：急性脑血管病 应激性高血糖 血清 胰岛素抵抗 发病机制 

分 类 号：R743.3[医药卫生—神经病学与精神病学] R587[医药卫生—临床医学]