早老性痴呆病——淀粉样蛋白Aβ研究进展  

Alzheimer's Disease:Advance in Researches on β-Amyloid Protein

作　　者：刘建辉[1] 包永明[1] 安利佳[1] 

机构地区：[1]大连理工大学化工学院生物工程系,大连,116012

出　　处：《生物医学工程学杂志》2003年第2期371-374,共4页Journal of Biomedical Engineering

摘　　要：早老性痴呆病因世界人口的老龄化而逐渐成为人们研究的热点。 β样淀粉蛋白 (Aβ)在神经系统中的过量沉积是老年痴呆病人的显著特征 ,本文简单综述了 Aβ的形成途径及影响因素 。The pathogenesis and treatment of Alzheimer's disease (AD) have developed into the frontier with the aging of people in the world. Meanwhile, they are the most difficult steps in the research on this degenerative disease of the nervous system. The over deposition of β amyloid protein in nervous system is the most important feature. The formation and influencing factors of β amyloid protein are summarized in this paper. Furthermore, the methods and advance in treatment of AD are reviewed especially.

关 键 词：早老性痴呆病 淀粉样蛋白Aβ 研究进展 发病机制 淀粉样前体蛋白 脑退行性疾病 

分 类 号：R749.16[医药卫生—神经病学与精神病学]