Scotopic Sensitivity of Central Retina in Early Age-Related Macular Degeneration  

作　　者：Changzheng Chen, Lezheng Wu, Futian Jiang, Jiongji Liang, De-Zheng WuZhongshan Ophthalmic Center, Sun Yat-sen University, Guangzhou 510060, China 

出　　处：《Eye Science》2003年第1期15-19,共5页眼科学报（英文版）

摘　　要：Purpose: To test scotopic sensitivity and investigate whether there is rod systemdysfunction in the central retina in early age - related macular degeneration (AMD).Methods:Scotopic (450 nm stimulus) and photopic (white light stimulus) sensitivity in24 patients with early AMD was measured at 81 loci in central 25° of retina, andcompared with the age - match normal controls.Results: Mean scotopic sensitivity of AMD patients was significantly lower than that ofthe normal controls. The patients of reduced scotopic sensitivity were more than those ofreduced photopic sensitivity. Scotopic sensitivity deficit decreased with increasingeccentricity with the greatest deficit was 2. 5°to 5.0°.Conclusions: Scotopic sensitivity was decreased in the early stage of AMD. Theparafoveal rod cells were selectively damaged in AMD. Scotopic sensitivity testing inmacula may be a useful tool to diagnose and measure the fundus dysfunction of AMD.Purpose: To test scotopic sensitivity and investigate whether there is rod system dysfunction in the central retina in early age - related macular degeneration (AMD). Methods: Scotopic(450 nm stimulus) and photopic (white light stimulus) sensitivity in 24 patients with early AMD was measured at 81 loci in central 25° of retina, and compared with the age - match normal controls.Results: Mean scotopic sensitivity of AMD patients was significantly lower than that of the normal controls. The patients of reduced scotopic sensitivity were more than those of reduced photopic sensitivity. Scotopic sensitivity deficit decreased with increasing eccentricity with the greatest deficit was 2. 5° to 5. 0°.Conclusions: Scotopic sensitivity was decreased in the early stage of AMD. The parafoveal rod cells were selectively damaged in AMD. Scotopic sensitivity testing in macula may be a useful tool to diagnose and measure the fundus dysfunction of AMD. Eye Science 2003; 19: 15 - 19.

关 键 词：暗适应敏感性 视网膜中央 年龄相关性斑点恶化 视功能损害 

分 类 号：R774.1[医药卫生—眼科]