犬的动脉导管未闭模型建立失败总结  

Evaluation of 11 failure cases of canine model of patent ductus arteriosus

作　　者：汤敬东[1] 熊江[1] 高嵩[1] 景在平[1] 黄晟[1] 贾宝成[1] 裴强[1] 

机构地区：[1]第二军医大学长海医院血管外科暨全军血管外科研究所,上海200433

出　　处：《介入放射学杂志》2003年第4期291-293,共3页Journal of Interventional Radiology

摘　　要：目的　为了更好地开展动脉导管未闭动物模型建立工作 ,对实验中失败的 11条模型犬进行总结分析。方法　回顾性总结实验总例数 40条模型犬中 11条模型失败的原因。结果　 11条模型犬中麻醉失败 3条 ,手术失败 5条 ,围手术期处理不当失败 2条 ,原因不明死亡 1条。结论　动物模型建立与人的手术操作一样 ,随着操作的熟练和程序化 ,动脉导管未闭的犬模型建立的成功率也将随之提高。Objective To construct a canine patent ductus arteriosus model for studying. Methods 11 failure cases of canine model of patent ductus arteriosus were summarized to analyize the reason for failure. Results 3 cases failed during anaesthesia, 5 failed for operation, 2 due to nursing after operation, 1 for unknown reason.Conclusions The successful rate of animal model construction will be raised according to the improvement of the skillful and programmed procedure.

关 键 词：动脉导管未闭 动物模型 先天性疾病 麻醉 手术方法 

分 类 号：R-332[医药卫生]