乳斑与腹膜转移癌的相关性研究进展  

Progress in Relevance of Milky Spots and Peritoneal Carcinomatosis

作　　者：刘九洋[1] 李雁[1] 

机构地区：[1]武汉大学中南医院肿瘤科肿瘤生物学行为湖北省重点实验室湖北省肿瘤医学临床研究中心,武汉430071

出　　处：《肿瘤防治研究》2015年第6期618-621,共4页Cancer Research on Prevention and Treatment

基　　金：国家自然科学基金创新群体项目(20921062);教育部博士学科点专项科研基金(20120141110042)

摘　　要：乳斑(milky spots,MS)广泛存在于哺乳动物腹膜,主要组成细胞包括腹膜间皮细胞、血管内皮细胞、不同成熟阶段的巨噬细胞、B淋巴细胞、T淋巴细胞、肥大细胞和基质细胞。腹腔恶性肿瘤细胞从原发灶脱落,种植在乳斑形成微转移灶,最终形成腹膜转移癌(peritoneal carcinomatosis,PC)。本文就乳斑的大体解剖(形态、大小、分布)、组织学特征、生理功能以及病理反应方面进行综述,以全面系统地认识乳斑,进一步了解乳斑与腹膜转移癌的关系。Milky spots(MS) are widely located in mammalian peritonea and mainly composed of mesothelial cells,vascular endothelial cells,macrophages in different stages of maturation,B-lymphocytes,T-lymphocytes,mast cells and stromal cells.Peritoneal malignant tumor cells enter MS as they exfoliate from primary tumor lesions,colonize within them,and establish micro-metastasis,leading to peritoneal carcinomatosis(PC).This review summarizes the anatomy,histology,physiology and pathology of MS and explores the relationship between MS and PC.

关 键 词：乳斑 腹膜 腹膜转移癌 

分 类 号：R735.5[医药卫生—肿瘤]