腹膜后肿瘤临床病理特征与诊治分析  

Clinicopathological Features and Diagnosis of Retroperitoneal Tumor

作　　者：苗成利[1] 何远翔[1] 李玉坤[2] 蒋彦永[2] 于军辉[3] 刘星[3] 罗成华[1] 

机构地区：[1]北京大学国际医院腹膜后肿瘤中心,北京102206 [2]中国人民解放军总医院普外科,北京100039 [3]首都医科大学附属北京世纪坛医院肿瘤外科三病区,北京100038

出　　处：《肿瘤防治研究》2015年第8期797-800,共4页Cancer Research on Prevention and Treatment

摘　　要：目的探讨腹膜后肿瘤的临床病理特点,总结腹膜后肿瘤诊治经验。方法回顾性分析了1975年9月—2014年12月间收集的687例腹膜后肿瘤患者资料,并进行临床病理特征及术后复发影响因素的分析。结果 687例腹膜后肿瘤患者中,良性173例(25.2%),交界性44例(6.4%),恶性470例(68.4%)。原发性腹膜后恶性肿瘤中常见的为脂肪肉瘤、平滑肌肉瘤、恶性纤维组织细胞瘤,分别占全部腹膜后肿瘤11.6%、8.7%、4.4%。良性肿瘤常见的为畸胎瘤,占全部肿瘤5%。原发性肿瘤592例,占86.2%。继发性肿瘤95例,占13.8%。腹膜后肿瘤临床表现多样,术中出血多,术中联合脏器切除的概率高。肿瘤性质、肿瘤切除程度、肿瘤分化程度是腹膜后肿瘤术后复发的主要影响因素(P<0.05)。肿瘤切除愈彻底,复发时间愈晚。结论提高腹膜后恶性肿瘤的完全切除率,降低腹膜后肿瘤术后复发,是治疗腹膜后肿瘤的关键措施。Objective To discuss the clinicopathological characteristics of retroperitoneal tumors(RPT), and summarize the experience of diagnosis and treatment. Methods We reviewed and analyzed the data of 687 RPT patients between September 1975 to December 2014. Results RPT pathological type was complex: benign tumour: 173 cases, low-grade malignant tumor:44 cases, and malignant tumor: 470 cases. The common primary malignant RPT was liposarcoma(11.6%), leiomyosarcoma(8.7%), malignant fibrous histiocytoma(4.4%). Tumor pathological type was also complex: common benign tumor was teratoma: 5.0%, total benign tumor: 25.2%, borderline tumor: 6.4%, malignant tumor: 68.4%. Primary RPT(592 cases)accounted for 86.2%. Secondary RPT(95 cases)accounted for 13.8%. The clinical manifestation of RPT was complex: the incidence of hemorrhage during operation and viscera combined resection was high. Tumor characteristic, resection degree, differentiation degree were the influence factors for postoperative recurrence of RPT(P<0.05). Conclusion Improving the complete resection of retroperitoneal malignant tumor is the main measure to reduce tumor recurrence and treat the retroperitoneal tumors.

关 键 词：腹膜后肿瘤 脂肪肉瘤 COX回归分析 

分 类 号：R735.4[医药卫生—肿瘤]