高相对分子质量唾液粘蛋白保护牙釉质酸蚀脱矿的超微观察  

The effects of high relative molecular mass salivary mucin on the protection of tooth enamel against demineralization observed by electronic microscopy

作　　者：徐燕[1] 乐进秋[2] 江汉[2] 

机构地区：[1]安徽医科大学口腔医学院,合肥230032 [2]湖北武汉大学口腔医学院

出　　处：《实用口腔医学杂志》2004年第1期111-114,共4页Journal of Practical Stomatology

基　　金：国家自然科学基金资助编号:391 70 31 1 78

摘　　要：目的 :观察人类高相对分子质量唾液粘蛋白 (MG1)及全唾液在体外形成的获得性膜能否减少有机酸在牙面的脱矿作用。方法 :采用MG1和全唾液溶液体外孵育釉质实验面以形成获得性膜 ,再以 3 4mmol/L枸橼酸处理釉质实验面 1min ,扫描电镜观察釉质表面形态的改变。结果 :有获得性膜区域釉质实验面相对平滑 ,基本无脱矿及轻微脱矿 ,可见正常釉质表面形态 ,无获得性膜区域则是蜂巢状大面积脱矿。结论Objective: To observe the effect of purified high rela ti ve molecular mass mucin(MG1) pellicle on the protection of human dental enamel against demineralization.Methods: MGI was extracted from human saliva and purified.MGI pellicle and whole saliva pellicle were formed on dental enamel samples in vitro ,Then The samples were treated by 34 mmol/L citric acid for 1 min.The demineralization of the samples was observed by scanning electronic microscopy(SEM). Results:After treatment by the acid the enamel surfaces covered by MGI pellicles or whol e saliva pellicle showed relatively smooth and normal enamel morphological feat ures, on the contrary the surface without pellicle showed large area of deminer alization and bee nest like appearance. Conclusion: The data indicate that the MG1 in enamel pellicle contribute to its protective effec ts against acidic attack on the enamel surface.

关 键 词：唾液 粘蛋白 牙釉质 酸蚀 脱矿 获得性膜 

分 类 号：R780.1[医药卫生—口腔医学]