肝病患者血清单胺氧化酶活性水平观察  

Observation of serum monoamine oxidase activity in hepatopathy

作　　者：张凤菊[1] 翟春玺[1] 

机构地区：[1]山东省聊城市第二人民医院,山东临清252600

出　　处：《现代中西医结合杂志》2004年第4期441-441,490,共2页Modern Journal of Integrated Traditional Chinese and Western Medicine

摘　　要：目的　了解肝病患者单胺氧化酶 (MAO)活性水平及其动态改变。方法　采用快速比色法检测 187例肝病患者MAO活性 ,并以MAO活性 >4 0U/mL判为阳性。结果　 187例肝病患者的MAO活性高于正常对照组 (P <0 .0 1)。结论　血清MAO增高程度与肝脏结缔组织增生密切相关 ,其含量与病变严重程度有关。提示血清MAO活性的测定有助于肝病的诊断和鉴别诊断 ,尤其是肝硬化的早期诊断。同时对心衰引起肝淤血患者的疗效观察和预后判断有一定的帮助意义。Objective It is to observe the activity of serum monoamine oxidase (MAO) and its dynamic change in hepatopath. Methods MAO in 187 cases of hepatopath were measured with tachycolorimetry and the value more than 40*!U/mL was thought to be positive. Results The activities of MAO in 187 cases of hepatopath were higher than that in normal control group (P<0.01). Conclusion Increasing of MAO is closely related to the hyperplasia of connective tissue in liver. The content of MAO is related to the degree of hepatopathy. The measurement of MAO conduces to the diagnosis and differential diagnosis of hepatopathy, especially for early diagnosis of cirrhosis of liver. Furthermore, it is helpful to observation of curative effect and prognosis of hepatic congestion owing to cardiac failure.

关 键 词：单胺氧化酶 肝硬化 肝纤维化 

分 类 号：R575[医药卫生—消化系统]